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CTSW

The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. [provided by RefSeq]
Full Name
cathepsin W
Function
May have a specific function in the mechanism or regulation of T-cell cytolytic activity.

(Microbial infection) Plays a role during influenza virus infection in lungs cells ex vivo. Acts at the level of virus entering host cytoplasm from late endosome.
Biological Process
Immune response Source: ProtInc
Platelet degranulation Source: Reactome
Proteolysis involved in cellular protein catabolic process Source: GO_Central
Cellular Location
Endoplasmic reticulum

Anti-CTSW antibodies

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Target: CTSW
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBWJC-3441
Application*: WB
Target: CTSW
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-1777
Application*: WB, IP, IF, E
Target: CTSW
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-0623
Application*: WB, IH
Target: CTSW
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBLC204-LY
Application*: C, WB
Target: CTSW
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBCNC-495
Application*: IH, WB
Target: CTSW
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4A8
Application*: E, WB
Target: CTSW
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 39-2B6
Application*: C, WB
Target: CTSW
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 1B1
Application*: WB, IP, IF, P
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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