CTSW
The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. [provided by RefSeq]
Full Name
cathepsin W
Function
May have a specific function in the mechanism or regulation of T-cell cytolytic activity.
(Microbial infection) Plays a role during influenza virus infection in lungs cells ex vivo. Acts at the level of virus entering host cytoplasm from late endosome.
(Microbial infection) Plays a role during influenza virus infection in lungs cells ex vivo. Acts at the level of virus entering host cytoplasm from late endosome.
Biological Process
Immune response Source: ProtInc
Platelet degranulation Source: Reactome
Proteolysis involved in cellular protein catabolic process Source: GO_Central
Platelet degranulation Source: Reactome
Proteolysis involved in cellular protein catabolic process Source: GO_Central
Cellular Location
Endoplasmic reticulum
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Anti-CTSW antibodies
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Target: CTSW
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-0623
Application*: WB, IP, IF
Target: CTSW
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLC204-LY
Application*: WB, IP, IF, E
Target: CTSW
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBCNC-495
Application*: WB, IP, IF
Target: CTSW
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-1777
Application*: WB, IP, IF, P
Target: CTSW
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4A8
Application*: E, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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