DCTD
The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Full Name
DCMP Deaminase
Function
Supplies the nucleotide substrate for thymidylate synthetase.
Biological Process
dTMP biosynthetic process Source: GO_Central
dUMP biosynthetic process Source: GO_Central
Nucleobase-containing small molecule interconversion Source: Reactome
Pyrimidine nucleotide metabolic process Source: ProtInc
dUMP biosynthetic process Source: GO_Central
Nucleobase-containing small molecule interconversion Source: Reactome
Pyrimidine nucleotide metabolic process Source: ProtInc
Cellular Location
Cytosol
View more
Anti-DCTD antibodies
+ Filters
Loading...
CompareTarget: DCTD
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: 4B9
Application*: E, WB, P
Target: DCTD
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBYCD-185
Application*: WB, IP, IF, E
Target: DCTD
Specificity: Human
More Infomation
Hot products 
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
Online Inquiry