EPB41L3

EPB41L3 (Erythrocyte Membrane Protein Band 4.1 Like 3) is a Protein Coding gene. Diseases associated with EPB41L3 include Benign Meningioma and Bejel. Among its related pathways are Transmission across Chemical Synapses and Protein-protein interactions at synapses. Gene Ontology (GO) annotations related to this gene include actin binding and structural constituent of cytoskeleton. An important paralog of this gene is EPB41L2.

Full Name

erythrocyte membrane protein band 4.1-like 3

Research Area

Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N-methyltransferases, including PRMT3 and PRMT5.

Biological Process

Actomyosin structure organization Source: GO_Central
Apoptotic process Source: UniProtKB-KW
Cortical actin cytoskeleton organization Source: InterPro
Cortical cytoskeleton organization Source: BHF-UCL
Myelin maintenance Source: BHF-UCL
Neuron projection morphogenesis Source: BHF-UCL
Paranodal junction assembly Source: BHF-UCL
Protein localization to juxtaparanode region of axon Source: BHF-UCL
Protein localization to paranode region of axon Source: BHF-UCL
Protein localization to plasma membrane Source: BHF-UCL
Regulation of cell growth Source: InterPro
Regulation of cell shape Source: BHF-UCL

Cellular Location

Cytoskeleton; Cytoplasm; Cell membrane; Cell junction. Detected in the cytoplasm of actively dividing cells.