GFRA4
The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Full Name
GDNF Family Receptor Alpha 4
Function
Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
Biological Process
Negative regulation of ossification Source: Ensembl
Nervous system development Source: GO_Central
Nervous system development Source: GO_Central
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Anti-GFRA4 antibodies
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Target: GFRA4
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBFYH-3432
Application*: E, IH
Target: GFRA4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1307
Application*: WB: 1:500~1:1000 ELISA: 1:10000
Target: GFRA4
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: RM0244-1M21
Application*: WB
Target: GFRA4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3P34
Application*: WB
Target: GFRA4
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 1M21
Application*: IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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