GIP

This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. [provided by RefSeq, Jul 2008]
Full Name
Gastric Inhibitory Polypeptide
Function
Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.
Biological Process
Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: BHF-UCL
Adult locomotory behavior Source: Ensembl
Digestive system development Source: Ensembl
Endocrine pancreas development Source: Ensembl
Exploration behavior Source: Ensembl
Female pregnancy Source: Ensembl
Gastric inhibitory peptide signaling pathway Source: BHF-UCL
Long-term synaptic potentiation Source: Ensembl
Memory Source: Ensembl
Positive regulation of cAMP-mediated signaling Source: Ensembl
Positive regulation of glucagon secretion Source: Ensembl
Positive regulation of glucose transmembrane transport Source: Ensembl
Positive regulation of insulin secretion Source: Ensembl
Regulation of fatty acid biosynthetic process Source: InterPro
Regulation of insulin secretion Source: ParkinsonsUK-UCL
Response to acidic pH Source: Ensembl
Response to amino acid Source: Ensembl
Response to axon injury Source: Ensembl
Response to drug Source: Ensembl
Response to glucose Source: Ensembl
Response to lipid Source: Ensembl
Response to organic cyclic compound Source: Ensembl
Response to peptide hormone Source: Ensembl
Response to selenium ion Source: Ensembl
Response to starvation Source: GO_Central
Sensory perception of pain Source: Ensembl
Signal transduction Source: ProtInc
Triglyceride homeostasis Source: Ensembl
Cellular Location
Secreted
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Anti-GIP antibodies

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Target: GIP
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CAP840
Application*: ICC, IHC, IP, WB
Target: GIP
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CAP841
Application*: ICC, IHC, IP, WB
Target: GIP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: NA
Application*: ELISA, WB, IHC
Target: GIP
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLG1-1174
Application*: E, WB
Target: GIP
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLG1-1172
Application*: E, P
Target: GIP
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLG1-1171
Application*: E, IH, WB
Target: GIP
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLG1-1170
Application*: E, IH
Target: GIP
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLG1-1169
Application*: E
Target: GIP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 911205
Application*: IH
Target: GIP
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5
Application*: E, IC/IF
Target: GIP
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-0362
Application*: E, IF
Target: GIP
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-0361
Application*: E, IH, P
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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