GIP

This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. [provided by RefSeq, Jul 2008]

Gastric Inhibitory Polypeptide

Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.

Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: BHF-UCL
Adult locomotory behavior Source: Ensembl
Digestive system development Source: Ensembl
Endocrine pancreas development Source: Ensembl
Exploration behavior Source: Ensembl
Female pregnancy Source: Ensembl
Gastric inhibitory peptide signaling pathway Source: BHF-UCL
Long-term synaptic potentiation Source: Ensembl
Memory Source: Ensembl
Positive regulation of cAMP-mediated signaling Source: Ensembl
Positive regulation of glucagon secretion Source: Ensembl
Positive regulation of glucose transmembrane transport Source: Ensembl
Positive regulation of insulin secretion Source: Ensembl
Regulation of fatty acid biosynthetic process Source: InterPro
Regulation of insulin secretion Source: ParkinsonsUK-UCL
Response to acidic pH Source: Ensembl
Response to amino acid Source: Ensembl
Response to axon injury Source: Ensembl
Response to drug Source: Ensembl
Response to glucose Source: Ensembl
Response to lipid Source: Ensembl
Response to organic cyclic compound Source: Ensembl
Response to peptide hormone Source: Ensembl
Response to selenium ion Source: Ensembl
Response to starvation Source: GO_Central
Sensory perception of pain Source: Ensembl
Signal transduction Source: ProtInc
Triglyceride homeostasis Source: Ensembl

Secreted