GLP2R

The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq]
Full Name
glucagon-like peptide 2 receptor
Function
This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Biological Process
Adenylate cyclase-modulating G protein-coupled receptor signaling pathway Source: GO_Central
Cell surface receptor signaling pathway Source: InterPro
Positive regulation of cell population proliferation Source: ProtInc
Cellular Location
Cell membrane
Topology
Extracellular: 1-173
Helical: 174-198
Cytoplasmic: 199-210
Helical: 211-235
Extracellular: 236-261
Helical: 262-285
Cytoplasmic: 286-299
Helical: 300-321
Extracellular: 322-339
Helical: 340-362
Cytoplasmic: 363-386
Helical: 387-405
Extracellular: 406-417
Helical: 418-438
Cytoplasmic: 439-550
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Anti-GLP2R antibodies

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Mouse Anti-GLP2R Recombinant Antibody (CBLG1-1286) (CBMAB-G3838-LY)

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Target: GLP2R
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBLG1-1286
Application*: E, WB
Datasheet SDS

Mouse Anti-GLP2R Recombinant Antibody (CBLG1-1285) (CBMAB-G3837-LY)

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Target: GLP2R
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBLG1-1285
Application*: F, IF
Datasheet SDS

Mouse Anti-GLP2R Recombinant Antibody (CBLG1-1284) (CBMAB-G3836-LY)

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Target: GLP2R
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBLG1-1284
Application*: WB, IP, E
Datasheet SDS

Mouse Anti-GLP2R Recombinant Antibody (CBLG1-126) (CBMAB-G0525-LY)

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Target: GLP2R
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBLG1-126
Application*: E, WB
Datasheet SDS

Mouse Anti-GLP2R Recombinant Antibody (413801) (CBMAB-G0524-LY)

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Target: GLP2R
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 413801
Application*: F
Datasheet SDS

Human Recombinant GLP2R protein, hFc Tag (V2LY-0526-LY4331)

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Target: GLP2R
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-173
Tag: hFc Tag
Datasheet SDS

Cynomolgus Recombinant GLP2R protein, ECD, hFc Tag (V2LY-0526-LY1521)

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Target: GLP2R
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-173
Tag: hFc Tag
Datasheet SDS

Rabbit Anti-GLP2R Recombinant Antibody (CBLG1-1286) (V2LY-1225-LY1509)

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Target: GLP2R
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBLG1-1286
Application*: E, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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