loading...

GLP2R

The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq]

Full Name

glucagon-like peptide 2 receptor

Function

This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Biological Process

Adenylate cyclase-modulating G protein-coupled receptor signaling pathway Source: GO_Central
Cell surface receptor signaling pathway Source: InterPro
Positive regulation of cell population proliferation Source: ProtInc

Cellular Location

Cell membrane

Topology

Extracellular: 1-173
Helical: 174-198
Cytoplasmic: 199-210
Helical: 211-235
Extracellular: 236-261
Helical: 262-285
Cytoplasmic: 286-299
Helical: 300-321
Extracellular: 322-339
Helical: 340-362
Cytoplasmic: 363-386
Helical: 387-405
Extracellular: 406-417
Helical: 418-438
Cytoplasmic: 439-550

View more

Anti-GLP2R antibodies

+ Filters

Loading...

Mouse Anti-GLP2R Recombinant Antibody (CBLG1-1286) (CBMAB-G3838-LY)

Compare

Target: GLP2R

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBLG1-1286

Application*: E, WB

Mouse Anti-GLP2R Recombinant Antibody (CBLG1-1285) (CBMAB-G3837-LY)

Compare

Target: GLP2R

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBLG1-1285

Application*: WB

Mouse Anti-GLP2R Recombinant Antibody (CBLG1-1284) (CBMAB-G3836-LY)

Compare

Target: GLP2R

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBLG1-1284

Application*: E, F

Mouse Anti-GLP2R Recombinant Antibody (CBLG1-126) (CBMAB-G0525-LY)

Compare

Target: GLP2R

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBLG1-126

Application*: E, WB

Mouse Anti-GLP2R Recombinant Antibody (413801) (CBMAB-G0524-LY)

Compare

Target: GLP2R

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 413801

Application*: F

More Infomation

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

online inquiry

Online Inquiry

Happy Holidays