HCFC2
This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described.
Full Name
Host Cell Factor C2
Biological Process
Chromatin remodeling Source: GO_Central
Negative regulation of transcription by RNA polymerase II Source: UniProtKB
Regulation of transcription, DNA-templated Source: GO_Central
Regulation of transcription by RNA polymerase II Source: ProtInc
Viral process Source: ProtInc
Negative regulation of transcription by RNA polymerase II Source: UniProtKB
Regulation of transcription, DNA-templated Source: GO_Central
Regulation of transcription by RNA polymerase II Source: ProtInc
Viral process Source: ProtInc
Cellular Location
Cytoplasm; Nucleus
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Anti-HCFC2 antibodies
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Target: HCFC2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-0770
Application*: IF, WB
Target: HCFC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0768
Application*: WB, IH, IF
Target: HCFC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-3026
Application*: DB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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