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HSPG2

HSPG2 is the perlecan protein, which consists of a core protein to which three long chains of glycosaminoglycans (heparan sulfate or chondroitin sulfate) are attached. The perlecan protein is a large multidomain proteoglycan that binds to and cross-links many extracellular matrix components and cell-surface molecules. It has been shown that this protein interacts with laminin, prolargin, collagen type IV, FGFBP1, FBLN2, FGF7 and transthyretin, etc., and it plays essential roles in multiple biological activities. Perlecan is a key component of the vascular extracellular matrix, where it helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. It can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation. It is a major component of basement membranes, where it is involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. Mutations in this gene cause Schwartz-Jampel syndrome type 1, Silverman-Handmaker type of dyssegmental dysplasia, and tardive dyskinesia.

Anti-HSPG2 antibodies

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Rat Anti-HSPG2 Recombinant Antibody (CBFYH-2460) (CBMAB-H0753-FY)

Target: HSPG2
Host: Rat
Antibody Isotype: IgG2a, κ
Cross Reactivity: Mouse
Clone: CBFYH-2460
Application*: IF, IH

Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2463) (CBMAB-H0752-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Human
Clone: CBFYH-2463
Application*: E, IH, WB

Rat Anti-HSPG2 Recombinant Antibody (CBFYH-2461) (CBMAB-H0751-FY)

Target: HSPG2
Host: Rat
Antibody Isotype: IgG2a, κ
Cross Reactivity: Mouse
Clone: CBFYH-2461
Application*: IC, IH, IP, WB

Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2462) (CBMAB-H0750-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Mammalian
Clone: CBFYH-2462
Application*: E, R, WB

Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2471) (CBMAB-H3484-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Cattle, Human
Clone: CBFYH-2471
Application*: WB, IP, E, P, C, AP, IF

Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2470) (CBMAB-H3483-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1, κ
Cross Reactivity: Cattle
Clone: CBFYH-2470
Application*: E, C, P, IP, WB

Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2469) (CBMAB-H3482-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Cattle, Human
Clone: CBFYH-2469
Application*: E, IH, IP, WB

Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2468) (CBMAB-H3481-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Human
Clone: CBFYH-2468
Application*: E, C, P, WB

Mouse Anti-HSPG2 (AA 4149-4391) Recombinant Antibody (CBFYH-2466) (CBMAB-H3480-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG
Cross Reactivity: Human
Clone: CBFYH-2466
Application*: E, WB

Rat Anti-HSPG2 Recombinant Antibody (CBFYH-2465) (CBMAB-H3479-FY)

Target: HSPG2
Host: Rat
Antibody Isotype: IgG2a, κ
Cross Reactivity: Cattle, Human, Mouse
Clone: CBFYH-2465
Application*: IC

Rat Anti-HSPG2 Recombinant Antibody (CBFYH-2464) (CBMAB-H3478-FY)

Target: HSPG2
Host: Rat
Antibody Isotype: IgG2a, κ
Cross Reactivity: Human
Clone: CBFYH-2464
Application*: IC, IH, IP, WB

Rat Anti-HSPG2 Recombinant Antibody (CBFYH-2459) (CBMAB-H3477-FY)

Target: HSPG2
Host: Rat
Antibody Isotype: IgG2a
Cross Reactivity: Cattle, Human, Mouse, Rat
Clone: CBFYH-2459
Application*: WB, IP, IH, IC

Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2458) (CBMAB-H3476-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Sheep, Cattle, Human
Clone: CBFYH-2458
Application*: WB, IP, E, P, C, AP

Rat Anti-HSPG2 Recombinant Antibody (CBFYH-2457) (CBMAB-H3475-FY)

Target: HSPG2
Host: Rat
Antibody Isotype: IgG2a
Cross Reactivity: Mouse, Cattle, Rat, Human
Clone: CBFYH-2457
Application*: IC, C, P, IP, WB

Rat Anti-HSPG2 Recombinant Antibody (CBFYH-2456) (CBMAB-H3474-FY)

Target: HSPG2
Host: Rat
Antibody Isotype: IgG2a, κ
Cross Reactivity: Mouse
Clone: CBFYH-2456
Application*: IF, C

Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2455) (CBMAB-H3473-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Cattle
Clone: CBFYH-2455
Application*: P, WB

Rat Anti-HSPG2 Recombinant Antibody (A7L6) (CBMAB-H3472-FY)

Target: HSPG2
Host: Rat
Antibody Isotype: IgG2a
Cross Reactivity: Mouse, Rat, Cattle, Human, Pig, Fish
Clone: A7L6
Application*: WB, IP, P, C, IC

Mouse Anti-HSPG2 Recombinant Antibody (5C9) (CBMAB-0248-CN)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1, κ
Cross Reactivity: Chicken, Quail
Clone: 5C9
Application*: E

Mouse Anti-HSPG2 (AA 4149-4391) Recombinant Antibody (CBFYH-2467) (CBMAB-H0660-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG
Cross Reactivity: Human
Clone: CBFYH-2467
Application*: E, IC, WB

Mouse Anti-HSPG2 (AA 3684-4391) Recombinant Antibody (CBFYE-1468) (CBMAB-E2097-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Human
Clone: CBFYE-1468
Application*: WB

Rat Anti-HSPG2 Recombinant Antibody (CBFYE-0130) (CBMAB-E0256-FY)

Target: HSPG2
Host: Rat
Antibody Isotype: IgG2a, κ
Cross Reactivity: Human, Mouse, Pig, Fish, Monkey
Clone: CBFYE-0130
Application*: F, P, IF

Mouse Anti-HSPG2 Recombinant Antibody (CBFYE-0129) (CBMAB-E0255-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1, κ
Cross Reactivity: Human, Cattle
Clone: CBFYE-0129
Application*: E, IH, IP, C

Mouse Anti-HSPG2 Recombinant Antibody (A76) (CBMAB-P0385-YC)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Cattle, Human
Clone: A76
Application*: E, WB, C, P, IP, AP

Mouse Anti-HSPG2 Recombinant Antibody (A74) (CBMAB-P0384-YC)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Cattle, Human
Clone: A74
Application*: E, WB, C, P, IP, AP

Mouse Anti-HSPG2 Recombinant Antibody (A71) (CBMAB-P0383-YC)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Cattle, Human
Clone: A71
Application*: E, IH, IP

Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2475) (CBMAB-H3488-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Human
Clone: CBFYH-2475
Application*: E, C, P, WB

Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2474) (CBMAB-H3487-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG
Cross Reactivity: Human
Clone: CBFYH-2474
Application*: E

Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2473) (CBMAB-H3486-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG
Cross Reactivity: Human
Clone: CBFYH-2473
Application*: WB, IC, C, E

Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2472) (CBMAB-H3485-FY)

Target: HSPG2
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Cattle
Clone: CBFYH-2472
Application*: E, C, IP, WB
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)