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HSPG2

HSPG2 is the perlecan protein, which consists of a core protein to which three long chains of glycosaminoglycans (heparan sulfate or chondroitin sulfate) are attached. The perlecan protein is a large multidomain proteoglycan that binds to and cross-links many extracellular matrix components and cell-surface molecules. It has been shown that this protein interacts with laminin, prolargin, collagen type IV, FGFBP1, FBLN2, FGF7 and transthyretin, etc., and it plays essential roles in multiple biological activities. Perlecan is a key component of the vascular extracellular matrix, where it helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. It can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation. It is a major component of basement membranes, where it is involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. Mutations in this gene cause Schwartz-Jampel syndrome type 1, Silverman-Handmaker type of dyssegmental dysplasia, and tardive dyskinesia.

Anti-HSPG2 antibodies

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Cat Product Name Target Host Antibody Isotype Cross Reactivity Clone Application*
CBMAB-H3488-FY Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2475) HSPG2 Mouse IgG1 Human CBFYH-2475 E, C, P, WB
CBMAB-H3487-FY Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2474) HSPG2 Mouse IgG Human CBFYH-2474 E
CBMAB-H3486-FY Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2473) HSPG2 Mouse IgG Human CBFYH-2473 WB, IC, C, E
CBMAB-H3485-FY Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2472) HSPG2 Mouse IgG1 Cattle CBFYH-2472 E, C, IP, WB
CBMAB-H3484-FY Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2471) HSPG2 Mouse IgG1 Cattle, Human CBFYH-2471 WB, IP, E, P, C, AP, IF
CBMAB-H3483-FY Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2470) HSPG2 Mouse IgG1, κ Cattle CBFYH-2470 E, C, P, IP, WB
CBMAB-H3482-FY Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2469) HSPG2 Mouse IgG1 Cattle, Human CBFYH-2469 E, IH, IP, WB
CBMAB-H3481-FY Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2468) HSPG2 Mouse IgG1 Human CBFYH-2468 E, C, P, WB
CBMAB-H3480-FY Mouse Anti-HSPG2 (AA 4149-4391) Recombinant Antibody (CBFYH-2466) HSPG2 Mouse IgG Human CBFYH-2466 E, WB
CBMAB-H3479-FY Rat Anti-HSPG2 Recombinant Antibody (CBFYH-2465) HSPG2 Rat IgG2a, κ Cattle, Human, Mouse CBFYH-2465 IC
CBMAB-H3478-FY Rat Anti-HSPG2 Recombinant Antibody (CBFYH-2464) HSPG2 Rat IgG2a, κ Human CBFYH-2464 IC, IH, IP, WB
CBMAB-H3477-FY Rat Anti-HSPG2 Recombinant Antibody (CBFYH-2459) HSPG2 Rat IgG2a Cattle, Human, Mouse, Rat CBFYH-2459 WB, IP, IH, IC
CBMAB-H3476-FY Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2458) HSPG2 Mouse IgG1 Sheep, Cattle, Human CBFYH-2458 WB, IP, E, P, C, AP
CBMAB-H3475-FY Rat Anti-HSPG2 Recombinant Antibody (CBFYH-2457) HSPG2 Rat IgG2a Mouse, Cattle, Rat, Human CBFYH-2457 IC, C, P, IP, WB
CBMAB-H3474-FY Rat Anti-HSPG2 Recombinant Antibody (CBFYH-2456) HSPG2 Rat IgG2a, κ Mouse CBFYH-2456 IF, C
CBMAB-H3473-FY Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2455) HSPG2 Mouse IgG1 Cattle CBFYH-2455 P, WB
CBMAB-H3472-FY Rat Anti-HSPG2 Recombinant Antibody (A7L6) HSPG2 Rat IgG2a Mouse, Rat, Cattle, Human, Pig, Fish A7L6 WB, IP, P, C, IC
CBMAB-H0660-FY Mouse Anti-HSPG2 (AA 4149-4391) Recombinant Antibody (CBFYH-2467) HSPG2 Mouse IgG Human CBFYH-2467 E, IC, WB
CBMAB-H0750-FY Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2462) HSPG2 Mouse IgG1 Mammalian CBFYH-2462 E, R, WB
CBMAB-E2097-FY Mouse Anti-HSPG2 (AA 3684-4391) Recombinant Antibody (CBFYE-1468) HSPG2 Mouse IgG1 Human CBFYE-1468 WB
CBMAB-E0256-FY Rat Anti-HSPG2 Recombinant Antibody (CBFYE-0130) HSPG2 Rat IgG2a, κ Human, Mouse, Pig, Fish, Monkey CBFYE-0130 F, P, IF
CBMAB-E0255-FY Mouse Anti-HSPG2 Recombinant Antibody (CBFYE-0129) HSPG2 Mouse IgG1, κ Human, Cattle CBFYE-0129 E, IH, IP, C
CBMAB-H0753-FY Rat Anti-HSPG2 Recombinant Antibody (CBFYH-2460) HSPG2 Rat IgG2a, κ Mouse CBFYH-2460 IF, IH
CBMAB-H0752-FY Mouse Anti-HSPG2 Recombinant Antibody (CBFYH-2463) HSPG2 Mouse IgG1 Human CBFYH-2463 E, IH, WB
CBMAB-H0751-FY Rat Anti-HSPG2 Recombinant Antibody (CBFYH-2461) HSPG2 Rat IgG2a, κ Mouse CBFYH-2461 IC, IH, IP, WB
CBMAB-P0385-YC Mouse Anti-HSPG2 Recombinant Antibody (A76) HSPG2 Mouse IgG1 Cattle, Human A76 E, WB, C, P, IP, AP
CBMAB-P0384-YC Mouse Anti-HSPG2 Recombinant Antibody (A74) HSPG2 Mouse IgG1 Cattle, Human A74 E, WB, C, P, IP, AP
CBMAB-P0383-YC Mouse Anti-HSPG2 Recombinant Antibody (A71) HSPG2 Mouse IgG1 Cattle, Human A71 E, IH, IP
CBMAB-0248-CN Mouse Anti-HSPG2 Recombinant Antibody (5C9) HSPG2 Mouse IgG1, κ Chicken, Quail 5C9 E
PEP-127579CQ Human HSPG2 Peptide (VGTRPSNH) HSPG2
PEP-029576CQ Human HSPG2 Peptide (AASISAVSL) HSPG2
PEP-029575CQ Human HSPG2 Peptide (SYVTSPQGFQF) HSPG2
PEP-187541CQ Mouse HSPG2 Peptide (DLVTGRSPGPNVAVNT) HSPG2
PEP-187540CQ Mouse HSPG2 Peptide (SQSVVHPVRIESSSPS) HSPG2
PEP-187539CQ Mouse HSPG2 Peptide (SPSHSQSVVHPVRIESSSPS) HSPG2
PEP-187538CQ Mouse HSPG2 Peptide (HSQSVVHPVRIESSSPS) HSPG2
PEP-187537CQ Mouse HSPG2 Peptide (RLNRVSPADSGEYSCQVT) HSPG2
PEP-187536CQ Mouse HSPG2 Peptide (LNRVSPADSGEYSCQVT) HSPG2
PEP-127578CQ Human HSPG2 Peptide (SGPYFWSLPSRFLGDK) HSPG2
PEP-127577CQ Human HSPG2 Peptide (IRASYAQQPAESRVSG) HSPG2
PEP-127576CQ Human HSPG2 Peptide (GTLIIRDVKESDQG) HSPG2
PEP-127575CQ Human HSPG2 Peptide (GGELRFTVTQRSQPG) HSPG2
PEP-127574CQ Human HSPG2 Peptide (SYVTSPQGF) HSPG2
PEP-127573CQ Human HSPG2 Peptide (DASPPPVKI) HSPG2
PEP-127572CQ Human HSPG2 Peptide (GLNLHTLLY) HSPG2
PEP-127571CQ Human HSPG2 Peptide (DSYGGSLRY) HSPG2
PEP-127570CQ Human HSPG2 Peptide (ATSPAGTAQAR) HSPG2
PEP-127569CQ Human HSPG2 Peptide (AMAPGAPQV) HSPG2
PEP-127568CQ Human HSPG2 Peptide (ALADLDELLIR) HSPG2
PEP-127567CQ Human HSPG2 Peptide (TTQSHVLLL) HSPG2
PEP-127566CQ Human HSPG2 Peptide (TQPIRIEPSSSQVAE) HSPG2
PEP-127565CQ Human HSPG2 Peptide (TQPIRIEPSSSQVA) HSPG2
PEP-127564CQ Human HSPG2 Peptide (RSIEYSPQL) HSPG2
PEP-127563CQ Human HSPG2 Peptide (RRFLVHDSF) HSPG2
PEP-127562CQ Human HSPG2 Peptide (PSVSPPIR) HSPG2
PEP-127561CQ Human HSPG2 Peptide (LPAKAQIHGGI) HSPG2
PEP-127560CQ Human HSPG2 Peptide (IPSHPRVTV) HSPG2
PEP-127559CQ Human HSPG2 Peptide (AAYGGKLRY) HSPG2
PEP-127558CQ Human HSPG2 Peptide (SPPYATTV) HSPG2
PEP-127557CQ Human HSPG2 Peptide (ALADLDELLIRA) HSPG2
PEP-127556CQ Human HSPG2 Peptide (TGEFTVEPVPEGAQ) HSPG2
PEP-127555CQ Human HSPG2 Peptide (LTGEFTVEPVPEGAQL) HSPG2
PEP-029574CQ Human HSPG2 Peptide (SEEPGHFSL) HSPG2
PEP-029573CQ Human HSPG2 Peptide (YGGELRFTVTQRSQPG) HSPG2
PEP-029572CQ Human HSPG2 Peptide (THFAPGDFQGF) HSPG2
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)