KCNS2

Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2.

Full Name

potassium voltage-gated channel modifier subfamily S member 2

Function

Biological Process

Potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Potassium ion transportISS:UniProtKB
Protein homooligomerizationIEA:InterPro
Regulation of delayed rectifier potassium channel activityISS:UniProtKB

Cellular Location

Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 or KCNB2.

Topology

Cytoplasmic: 1-184
Helical: 185-206
Extracellular: 207-225
Helical: 226-248
Cytoplasmic: 249-259
Helical: 260-280
Extracellular: 281-290
Helical: 291-311
Cytoplasmic: 312-326
Helical: 327-348
Extracellular: 349-361
Helical: 362-381
Extracellular: 382-388
Helical: 389-417
Cytoplasmic: 418-477

Anti-KCNS2 antibodies

Rabbit Anti-KCNS2 Recombinant Antibody (EG1773) (CBMAB-EN2112-LY)

Datasheet

SDS

Target: KCNS2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EG1773

Application*: WB: 1:500~1:1000 ELISA: 1:40000

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)