KCNS2
Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2.
Full Name
potassium voltage-gated channel modifier subfamily S member 2
Function
Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2.
Biological Process
Potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Potassium ion transportISS:UniProtKB
Protein homooligomerizationIEA:InterPro
Regulation of delayed rectifier potassium channel activityISS:UniProtKB
Potassium ion transportISS:UniProtKB
Protein homooligomerizationIEA:InterPro
Regulation of delayed rectifier potassium channel activityISS:UniProtKB
Cellular Location
Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 or KCNB2.
Topology
Cytoplasmic: 1-184
Helical: 185-206
Extracellular: 207-225
Helical: 226-248
Cytoplasmic: 249-259
Helical: 260-280
Extracellular: 281-290
Helical: 291-311
Cytoplasmic: 312-326
Helical: 327-348
Extracellular: 349-361
Helical: 362-381
Extracellular: 382-388
Helical: 389-417
Cytoplasmic: 418-477
Helical: 185-206
Extracellular: 207-225
Helical: 226-248
Cytoplasmic: 249-259
Helical: 260-280
Extracellular: 281-290
Helical: 291-311
Cytoplasmic: 312-326
Helical: 327-348
Extracellular: 349-361
Helical: 362-381
Extracellular: 382-388
Helical: 389-417
Cytoplasmic: 418-477
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Anti-KCNS2 antibodies
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CompareTarget: KCNS2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG1773
Application*: WB: 1:500~1:1000 ELISA: 1:40000
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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