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KCNS2

Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2.

Full Name

potassium voltage-gated channel modifier subfamily S member 2

Function

Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2.

Biological Process

Potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Potassium ion transportISS:UniProtKB
Protein homooligomerizationIEA:InterPro
Regulation of delayed rectifier potassium channel activityISS:UniProtKB

Cellular Location

Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 or KCNB2.

Topology

Cytoplasmic: 1-184
Helical: 185-206
Extracellular: 207-225
Helical: 226-248
Cytoplasmic: 249-259
Helical: 260-280
Extracellular: 281-290
Helical: 291-311
Cytoplasmic: 312-326
Helical: 327-348
Extracellular: 349-361
Helical: 362-381
Extracellular: 382-388
Helical: 389-417
Cytoplasmic: 418-477

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Anti-KCNS2 antibodies

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Rabbit Anti-KCNS2 Recombinant Antibody (EG1773) (CBMAB-EN2112-LY)

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Target: KCNS2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EG1773

Application*: WB: 1:500~1:1000 ELISA: 1:40000

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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