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LDB2

LIM-domain binding family are characterized by a conserved nuclear localization sequence, an amino-terminal homodimerization domain and a carboxy-terminal LIM interaction domain. LDB2 (LIM domain binding 2) belongs to the LIM-domain binding family. LDB2 may function in rhegmatogenous retinal detachment and coronary artery disease.
Full Name
LDB2
Function
Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors.
Biological Process
Epithelial structure maintenanceIEA:Ensembl
Hair follicle developmentIEA:Ensembl
Negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Nervous system developmentManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of cellular component biogenesisIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell migrationISS:UniProtKB
Regulation of kinase activityISS:UniProtKB
Somatic stem cell population maintenanceIEA:Ensembl
Cellular Location
Nucleus
PTM
Ubiquitinated by RLIM/RNF12, leading to its degradation by the proteasome.
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Anti-LDB2 antibodies

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Mouse Anti-LDB2 Recombinant Antibody (1C3) (CBMAB-A4893-LY)

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Target: LDB2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1C3
Application*: WB, E
Datasheet SDS

Mouse Anti-LDB2 Recombinant Antibody (CBYCL-181) (CBMAB-L0082-YC)

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Target: LDB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCL-181
Application*: E, IC, WB
Datasheet SDS

Mouse Anti-LDB2 Recombinant Antibody (CBYCL-180) (CBMAB-L0081-YC)

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Target: LDB2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYCL-180
Application*: E, WB
Datasheet SDS

Mouse Anti-LDB2 Recombinant Antibody (CBYJL-1330) (CBMAB-L0918-YJ)

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Target: LDB2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJL-1330
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-LDB2 Recombinant Antibody (1A3) (CBMAB-L0916-YJ)

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Target: LDB2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1A3
Application*: IF, WB
Datasheet SDS

Mouse Anti-LDB2 Antibody (1A10) (CBMAB-0612-YC)

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Target: LDB2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1A10
Application*: E, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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