NARS2

NARS2 is a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be
Full Name
Asparaginyl-TRNA Synthetase 2, Mitochondrial
Biological Process
Asparaginyl-tRNA aminoacylation Source: UniProtKB
Cellular Location
Mitochondrion matrix
Mitochondrion
Involvement in disease
Combined oxidative phosphorylation deficiency 24 (COXPD24):
An autosomal recessive mitochondrial disorder with wide phenotypic variability. Some patients have a milder form affecting only skeletal muscle, whereas others may have a more severe disorder, reminiscent of Alpers syndrome. Alpers syndrome is a progressive neurodegenerative disorder that presents in infancy or early childhood and is characterized by diffuse degeneration of cerebral gray matter.
Deafness, autosomal recessive, 94 (DFNB94):
A form of non-syndromic, sensorineural deafness characterized by prelingual, profound, bilateral hearing impairment. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
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Anti-NARS2 antibodies

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Mouse Anti-NARS2 Recombinant Antibody (8D10) (CBMAB-N1207-WJ)

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Target: NARS2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8D10
Application*: WB, IH
Datasheet SDS

Mouse Anti-NARS2 Recombinant Antibody (5A9) (CBMAB-N1206-WJ)

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Target: NARS2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5A9
Application*: WB, IH
Datasheet SDS

Mouse Anti-NARS2 Recombinant Antibody (10G5) (CBMAB-N1204-WJ)

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Target: NARS2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 10G5
Application*: WB
Datasheet SDS

Mouse Anti-NARS2 Recombinant Antibody (10C10) (CBMAB-N1203-WJ)

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Target: NARS2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10C10
Application*: WB
Datasheet SDS

Mouse Anti-NARS2 Recombinant Antibody (10E2) (CBMAB-N1201-WJ)

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Target: NARS2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 10E2
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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