NPM2

Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.
Full Name
nucleophosmin/nucleoplasmin, 2
Function
Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.
Biological Process
Blastocyst developmentManual Assertion Based On ExperimentIMP:UniProtKB
Chromatin remodelingManual Assertion Based On ExperimentIDA:UniProtKB
Oocyte differentiationManual Assertion Based On ExperimentIEP:UniProtKB
Positive regulation of DNA replicationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of meiotic nuclear divisionManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of exit from mitosisManual Assertion Based On ExperimentIMP:UniProtKB
Single fertilizationManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Nucleus
Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm.
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Anti-NPM2 antibodies

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Mouse Anti-NPM2 Recombinant Antibody (CBT4550) (V2LY-0625-LY1953)

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Target: NPM2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT4550
Application*: IH, IC
Datasheet SDS

Mouse Anti-NPM2 Recombinant Antibody (CBT4769) (V2LY-0625-LY1952)

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Target: NPM2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4769
Application*: IH, F
Datasheet SDS

Mouse Anti-NPM2 Recombinant Antibody (5E9) (CBMAB-N3162-WJ)

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Target: NPM2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5E9
Application*: E, IF, WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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