NPM2

Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.

Full Name

nucleophosmin/nucleoplasmin, 2

Function

Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.

Biological Process

Blastocyst developmentManual Assertion Based On ExperimentIMP:UniProtKB
Chromatin remodelingManual Assertion Based On ExperimentIDA:UniProtKB
Oocyte differentiationManual Assertion Based On ExperimentIEP:UniProtKB
Positive regulation of DNA replicationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of meiotic nuclear divisionManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of exit from mitosisManual Assertion Based On ExperimentIMP:UniProtKB
Single fertilizationManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Nucleus
Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm.

Anti-NPM2 antibodies

Mouse Anti-NPM2 Recombinant Antibody (5E9) (CBMAB-N3162-WJ)

Datasheet

SDS

Target: NPM2

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 5E9

Application*: E, IF, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)