PEBP1
This gene encodes a member of the phosphatidylethanolamine-binding family of proteins and has been shown to modulate multiple signaling pathways, including the MAP kinase (MAPK), NF-kappa B, and glycogen synthase kinase-3 (GSK-3) signaling pathways. The encoded protein can be further processed to form a smaller cleavage product, hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in neural development. This gene has been implicated in numerous human cancers and may act as a metastasis suppressor gene. Multiple pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Jul 2015]
Full Name
Phosphatidylethanolamine Binding Protein 1
Function
Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity).
Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.
HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor (By similarity).
Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.
HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor (By similarity).
Biological Process
Negative regulation of MAPK cascadeManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
View more
Anti-PEBP1 antibodies
+ Filters
Loading...
CompareTarget: PEBP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2G2-1F1
Application*: WB, E
Target: PEBP1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1D3-1B6
Application*: WB, E
Target: PEBP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Zebrafish
Clone: CBYC-P286
Application*: WB, P, IF, IC, IP
Target: PEBP1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2G2-1F1
Application*: E, WB
Target: PEBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 2D4D11
Application*: E, WB, IH
Target: PEBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2D4
Application*: WB
Target: PEBP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: D42F3
Application*: WB, P
Target: PEBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNR-537
Application*: E, WB
Target: PEBP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 6A175
Application*: IP, WB
Target: PEBP1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4B11
Application*: WB, E, IF
Target: PEBP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: EP2845Y
Application*: IC, P, WB
Target: PEBP1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 10BA5
Application*: E, WB
Target: PEBP1
Expressed Host: E. coli
Sequence: Amino Acid: 1-187
Target: PEBP1
Specificity: Human
Target: PEBP1
Specificity: Human
Target: PEBP1
Specificity: Human
Target: PEBP1
Specificity: Human
More Infomation
Hot products 
-
Mouse Anti-CD247 Recombinant Antibody (6B10.2) (CBMAB-C1583-YY)
-
Mouse Anti-BCL6 Recombinant Antibody (CBYY-0442) (CBMAB-0445-YY)
-
Mouse Anti-AHCYL1 Recombinant Antibody (V2-180270) (CBMAB-A1703-YC)
-
Mouse Anti-ESR1 Recombinant Antibody (Y31) (CBMAB-1208-YC)
-
Rabbit Anti-BRCA2 Recombinant Antibody (D9S6V) (CBMAB-CP0017-LY)
-
Rabbit Anti-CAMK2A Recombinant Antibody (BA0032) (CBMAB-0137CQ)
-
Rabbit Anti-CCL5 Recombinant Antibody (R0437) (CBMAB-R0437-CN)
-
Mouse Anti-CD33 Recombinant Antibody (P67.6) (CBMAB-C10189-LY)
-
Mouse Anti-BRD3 Recombinant Antibody (CBYY-0801) (CBMAB-0804-YY)
-
Mouse Anti-COL1A2 Recombinant Antibody (CF108) (V2LY-1206-LY626)
-
Mouse Anti-ADGRE5 Recombinant Antibody (V2-360335) (CBMAB-C2088-CQ)
-
Mouse Anti-GLP1R Recombinant Antibody (4F3) (CBMAB-G0521-LY)
-
Mouse Anti-DES Monoclonal Antibody (440) (CBMAB-AP1857LY)
-
Mouse Anti-DLC1 Recombinant Antibody (D1009) (CBMAB-D1009-YC)
-
Mouse Anti-C1QC Recombinant Antibody (CBFYC-0600) (CBMAB-C0654-FY)
-
Mouse Anti-ATP5F1A Recombinant Antibody (51) (CBMAB-A4043-YC)
-
Rabbit Anti-B2M Recombinant Antibody (CBYY-0059) (CBMAB-0059-YY)
-
Mouse Anti-A2M Recombinant Antibody (V2-178822) (CBMAB-A0036-YC)
-
Mouse Anti-CD24 Recombinant Antibody (ALB9) (CBMAB-0176CQ)
-
Rabbit Anti-ATF4 Recombinant Antibody (D4B8) (CBMAB-A3872-YC)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
Online Inquiry