PIGF

PIGF is a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described.

Phosphatidylinositol Glycan Anchor Biosynthesis Class F

Involved in GPI-anchor biosynthesis (PubMed:33386993).
It acts through the transfer of ethanolamine phosphate to the third mannose of GPI.

GPI anchor biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB

Endoplasmic reticulum membrane