POU2F2

POU2F2 is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters.
Full Name
POU class 2 homeobox 2
Function
Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') (PubMed:2904654, PubMed:7859290).
Regulates IL6 expression in B cells with POU2AF1 (By similarity).
Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression (PubMed:2901913, PubMed:2904654).
Modulates transcription transactivation by NR3C1, AR and PGR (PubMed:10480874).
Isoform 5
Activates the U2 small nuclear RNA (snRNA) promoter.
Biological Process
Cellular response to virusISS:UniProtKB
Humoral immune responseManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of interleukin-6 productionISS:UniProtKB
Positive regulation of transcription by RNA polymerase IIISS:UniProtKB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Nucleus
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Anti-POU2F2 antibodies

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Mouse Anti-POU2F2 Recombinant Antibody (IHC642) (CBMAB-MA205-YC)

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Target: POU2F2
Host: Mouse
Specificity: Human
Clone: IHC642
Application*: IH
Datasheet SDS

Mouse Anti-POU2F2 Recombinant Antibody (MRQ-2) (CBMAB-P2436-YC)

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Target: POU2F2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MRQ-2
Application*: C, P
Datasheet SDS

Rabbit Anti-POU2F2 Recombinant Antibody (CBCNC-686) (CBMAB-C4136-CN)

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Target: POU2F2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBCNC-686
Application*: E
Datasheet SDS

Mouse Anti-POU2F2 Recombinant Antibody (CBXO-0493) (CBMAB-O0264-CQ)

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Target: POU2F2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXO-0493
Application*: IH
Datasheet SDS

Mouse Anti-POU2F2 Recombinant Antibody (CBXO-0538) (CBMAB-O0263-CQ)

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Target: POU2F2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXO-0538
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-POU2F2 Recombinant Antibody (CBXO-0343) (CBMAB-O0260-CQ)

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Target: POU2F2
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: CBXO-0343
Application*: WB, IP, IF, P, E
Datasheet SDS

Mouse Anti-POU2F2 Recombinant Antibody (CBXO-0322) (CBMAB-O0259-CQ)

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Target: POU2F2
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXO-0322
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-POU2F2 (AA 1-200) Recombinant Antibody (CBXO-0497) (CBMAB-O0258-CQ)

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Target: POU2F2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: CBXO-0497
Application*: WB
Datasheet SDS

Human Anti-POU2F2 Recombinant Antibody (CBXO-0432) (CBMAB-O0072-CQ)

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Target: POU2F2
Host: Human
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBXO-0432
Application*: F
Datasheet SDS

Rat Anti-POU2F2 (AA 1-44) Recombinant Antibody (CBXO-0537) (CBMAB-O0023-CQ)

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Target: POU2F2
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse, Human
Clone: CBXO-0537
Application*: IS, WB
Datasheet SDS

Mouse Anti-POU2F2 Recombinant Antibody (3E3-6F9) (CBMAB-1889CQ)

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Target: POU2F2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3E3-6F9
Application*: WB, P
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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