PPM1G
PPM1G is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
Full Name
Protein Phosphatase, Mg2+/Mn2+ Dependent 1G
Biological Process
Peptidyl-threonine dephosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Protein dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell cycleManual Assertion Based On ExperimentTAS:ProtInc
Protein dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell cycleManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytoplasm
Membrane
Membrane
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Anti-PPM1G antibodies
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CompareTarget: PPM1G
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: k1G6
Application*: WB, E, IH, P
Target: PPM1G
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBYC-P556
Application*: WB, P, F, IC, IF
Target: PPM1G
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 9A211
Application*: E, ID, WB
Target: PPM1G
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1C12
Application*: IF, WB
Target: PPM1G
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: Full Length
Tag: GST Tag
Target: PPM1G
Expressed Host: E. coli
Sequence: Amino Acid: 317-546
Tag: His Tag
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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