PSMD13

PSMD13 (Proteasome 26S Subunit, Non-ATPase 13) is a protein coding gene. Among its related pathways are Cell Cycle, Mitotic and RET signaling.

Full Name

Proteasome 26S Subunit, Non-ATPase 13

Function

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

Biological Process

Meiosis IIEA:Ensembl
Proteasome-mediated ubiquitin-dependent protein catabolic process1 PublicationIC:ComplexPortal
Ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

cytosol
extracellular region
ficolin-1-rich granule lumen
membrane
nucleoplasm
nucleus
proteasome accessory complex
proteasome complex
proteasome regulatory particle
proteasome regulatory particle, lid subcomplex
secretory granule lumen