PTPN9

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. [provided by RefSeq]

Full Name

protein tyrosine phosphatase, non-receptor type 9

Function

Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus.

Biological Process

Negative regulation of neuron projection developmentManual Assertion Based On ExperimentIDA:MGI
Peptidyl-tyrosine dephosphorylationManual Assertion Based On ExperimentIDA:MGI
Positive regulation of protein localization to plasma membraneManual Assertion Based On ExperimentIDA:MGI
Protein dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm