RASAL2

This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Full Name

RAS Protein Activator Like 2

Function

Inhibitory regulator of the Ras-cyclic AMP pathway.

Biological Process

Biological Process adipose tissue developmentIEA:Ensembl
Biological Process gene expressionIEA:Ensembl
Biological Process multicellular organism growthIEA:Ensembl
Biological Process regulation of GTPase activityIEA:InterPro
Biological Process regulation of protein activation cascadeIEA:Ensembl
Biological Process response to dietary excessIEA:Ensembl
Biological Process response to glucoseIEA:Ensembl
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Cytosol