RASEF

The gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, cognitive disability, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
Full Name
RAS and EF-hand domain containing
Function
Binds predominantly GDP, and also GTP (PubMed:17448446).
Acts as a dynein adapter protein that activates dynein-mediated transport and dynein-dynactin motility on microtubules (PubMed:30814157).
Cellular Location
Cytoplasm, perinuclear region
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Anti-RASEF antibodies

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Rat Anti-RASEF Recombinant Antibody (3G260) (CBMAB-R1485-CN)

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Target: RASEF
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 3G260
Application*: IF, IH, IP, N, WB
Datasheet SDS

Mouse Anti-RASEF Recombinant Antibody (CBCNR-240) (CBMAB-R1490-CN)

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Target: RASEF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBCNR-240
Application*: WB, P
Datasheet SDS

Mouse Anti-RASEF Recombinant Antibody (CBCNR-239) (CBMAB-R1489-CN)

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Target: RASEF
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBCNR-239
Application*: E, WB, P
Datasheet SDS

Rabbit Anti-RASEF Recombinant Antibody (6k344) (CBMAB-R1486-CN)

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Target: RASEF
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 6k344
Application*: WB, ICC
Datasheet SDS

Mouse Anti-RASEF Recombinant Antibody (2Q278) (CBMAB-R1484-CN)

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Target: RASEF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 2Q278
Application*: E, WB
Datasheet SDS

Mouse Anti-RASEF Recombinant Antibody (2D5) (CBMAB-R1483-CN)

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Target: RASEF
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2D5
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-RASEF Recombinant Antibody (1H2) (CBMAB-R1482-CN)

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Target: RASEF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1H2
Application*: WB, IF
Datasheet SDS

rabbit Anti-RASEF Recombinant Antibody (10F658) (CBMAB-R1480-CN)

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Target: RASEF
Host: rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 10F658
Application*: WB
Datasheet SDS

Mouse Anti-RASEF Recombinant Antibody (10F13) (CBMAB-R1479-CN)

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Target: RASEF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10F13
Application*: E, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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