RPP30
RPP30 (Ribonuclease P/MRP Subunit P30) is a Protein Coding gene. Diseases associated with RPP30 include Omenn Syndrome. Among its related pathways are Gene Expression and tRNA processing. Gene Ontology (GO) annotations related to this gene include ribonuclease P activity.
Full Name
Ribonuclease P/MRP Subunit P30
Function
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:9037013, PubMed:9630247, PubMed:30454648).
Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).
Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).
Biological Process
Biological Process RNA phosphodiester bond hydrolysis, endonucleolyticManual Assertion Based On ExperimentIBA:GO_Central
Biological Process rRNA processingIEA:UniProtKB-KW
Biological Process tRNA 5'-leader removalManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process tRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process rRNA processingIEA:UniProtKB-KW
Biological Process tRNA 5'-leader removalManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process tRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus, nucleolus
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Anti-RPP30 antibodies
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CompareTarget: RPP30
Host: Mouse
Specificity: Human, Mouse, Rat
Clone: 8C289
Application*: WB
Target: RPP30
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Human
Clone: 2931D5a
Application*: WB, DB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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