S100A6
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008]
Full Name
S100 Calcium Binding Protein A6
Function
May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
Biological Process
Biological Process axonogenesis1 PublicationNAS:UniProtKB
Biological Process positive regulation of fibroblast proliferation1 PublicationNAS:UniProtKB
Biological Process signal transductionManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process positive regulation of fibroblast proliferation1 PublicationNAS:UniProtKB
Biological Process signal transductionManual Assertion Based On ExperimentTAS:UniProtKB
Cellular Location
Nucleus envelope
Cytoplasm
Cell membrane
Cytoplasm
Cell membrane
PTM
The N-terminus is blocked.
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Anti-S100A6 antibodies
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CompareTarget: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5A10
Application*: WB, IH
Target: S100A6
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2A6
Application*: WB, IH
Target: S100A6
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: D3H3W
Application*: WB, IP
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3E11-E9-D8
Application*: WB
Target: S100A6
Host: Mouse
Specificity: Human
Clone: CBXS-3349
Application*: E, WB
Target: S100A6
Host: Mouse
Specificity: Human
Clone: CBXS-2634
Application*: E, IC, IH, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1921
Application*: WB, IH
Target: S100A6
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1345
Application*: WB, IP, P, F, IF
Target: S100A6
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1344
Application*: WB, P, F, IF
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-1112
Application*: F, IF, IF
Target: S100A6
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXS-1089
Application*: E, EC, P
Target: S100A6
Host: Mouse
Specificity: Rat
Clone: CBXS-0088
Application*: WB, IC, P, C, E
Target: S100A6
Host: Mouse
Specificity: Mouse
Clone: CBXS-0087
Application*: WB, IC, P, C, E
Target: S100A6
Host: Mouse
Specificity: Human
Clone: CBXS-0086
Application*: WB, IC, P, C, E
Target: S100A6
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBXS-0085
Application*: E, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-0084
Application*: E, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle, Goat, Human, Pig, Rabbit, Rat
Clone: CBXS-6141
Application*: IC, IF, P, IP, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5487
Application*: E, IF
Target: S100A6
Host: Rabbit
Specificity: Human, Mouse, Rat, Monkey
Clone: CBXS-5382
Application*: WB, IP
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5202
Application*: WB, P, IF
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5131
Application*: WB, IH
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4835
Application*: E, WB, IH, IF
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5876
Application*: WB, E, IH, P
Target: S100A6
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-5829
Application*: WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBXS-5601
Application*: WB
Target: S100A6
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1237
Application*: WB, IP, F, IF
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C2104
Application*: E, IF, IH, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7D11
Application*: E, IH, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 6D1
Application*: E, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3BA7
Application*: E, M, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3BA6
Application*: E, M, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4337
Application*: IH
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CF381
Application*: ELISA, WB, IF, IHC
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 6B5
Application*: WB, E, IF, P
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7D11A8
Application*: WB, E, IH, P
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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