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S100A6

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008]
Full Name
S100 Calcium Binding Protein A6
Function
May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
Biological Process
Biological Process axonogenesis1 PublicationNAS:UniProtKB
Biological Process positive regulation of fibroblast proliferation1 PublicationNAS:UniProtKB
Biological Process signal transductionManual Assertion Based On ExperimentTAS:UniProtKB
Cellular Location
Nucleus envelope
Cytoplasm
Cell membrane
PTM
The N-terminus is blocked.

Anti-S100A6 antibodies

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Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5131
Application*: WB, IH
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5202
Application*: WB, P, IF
Target: S100A6
Host: Rabbit
Specificity: Human, Mouse, Rat, Monkey
Clone: CBXS-5382
Application*: WB, IP
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5487
Application*: E, IF
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle, Goat, Human, Pig, Rabbit, Rat
Clone: CBXS-6141
Application*: IC, IF, P, IP, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-0084
Application*: E, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBXS-0085
Application*: E, WB
Target: S100A6
Host: Mouse
Specificity: Human
Clone: CBXS-0086
Application*: WB, IC, P, C, E
Target: S100A6
Host: Mouse
Specificity: Mouse
Clone: CBXS-0087
Application*: WB, IC, P, C, E
Target: S100A6
Host: Mouse
Specificity: Rat
Clone: CBXS-0088
Application*: WB, IC, P, C, E
Target: S100A6
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXS-1089
Application*: E, EC, P
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-1112
Application*: F, IF, IF
Target: S100A6
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1344
Application*: WB, P, F, IF
Target: S100A6
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1345
Application*: WB, IP, P, F, IF
Target: S100A6
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1921
Application*: WB, IH
Target: S100A6
Host: Mouse
Specificity: Human
Clone: CBXS-2634
Application*: E, IC, IH, WB
Target: S100A6
Host: Mouse
Specificity: Human
Clone: CBXS-3349
Application*: E, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3E11-E9-D8
Application*: WB
Target: S100A6
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: D3H3W
Application*: WB, IP
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CF381
Application*: ELISA, WB, IF, IHC
Target: S100A6
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 6D1
Application*: E, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3BA7
Application*: E, M, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3BA6
Application*: E, M, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 6B5
Application*: WB, E, IF, P
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7D11A8
Application*: WB, E, IH, P
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5A10
Application*: WB, IH
Target: S100A6
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2A6
Application*: WB, IH
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4835
Application*: E, WB, IH, IF
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5876
Application*: WB, E, IH, P
Target: S100A6
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-5829
Application*: WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBXS-5601
Application*: WB
Target: S100A6
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1237
Application*: WB, IP, F, IF
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C2104
Application*: E, IF, IH, WB
Target: S100A6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7D11
Application*: E, IH, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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