SEPT3

This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]

septin 3

Filament-forming cytoskeletal GTPase (By similarity).
May play a role in cytokinesis (Potential).

Biological Process cytoskeleton-dependent cytokinesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein localizationManual Assertion Based On ExperimentIBA:GO_Central

Cytoplasm
Cytoplasm, cytoskeleton
Synapse

Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91 (By similarity).