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SIGLECF

Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).
Full Name
sialic acid binding Ig-like lectin F
Cellular Location
Integral component of membrane
Topology
Helical: 350-375
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Anti-SIGLECF antibodies

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Rat Anti-SIGLECF Recombinant Antibody (CBXS-2581) (CBMAB-S5337-CQ)

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Target: SIGLECF
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBXS-2581
Application*: N, WB
Datasheet SDS

Rat Anti-SIGLECF Recombinant Antibody (CBXS-1717) (CBMAB-S4551-CQ)

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Target: SIGLECF
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXS-1717
Application*: N
Datasheet SDS

Rat Anti-SIGLECF Recombinant Antibody (CBXS-1716) (CBMAB-S4550-CQ)

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Target: SIGLECF
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBXS-1716
Application*: WB
Datasheet SDS

Rat Anti-SIGLECF Recombinant Antibody (ES22-10D8) (CBMAB-S0442-CQ)

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Target: SIGLECF
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: ES22-10D8
Application*: F
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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