SMNDC1
This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. [provided by RefSeq]
Full Name
SMNDC1
Function
Involved in spliceosome assembly.
Biological Process
Biological Process apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process mRNA processingIEA:UniProtKB-KW
Biological Process RNA splicing, via transesterification reactionsManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process mRNA processingIEA:UniProtKB-KW
Biological Process RNA splicing, via transesterification reactionsManual Assertion Based On ExperimentTAS:UniProtKB
Cellular Location
Nucleus speckle
Nucleus, Cajal body
Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies.
Nucleus, Cajal body
Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies.
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Anti-SMNDC1 antibodies
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Target: SMNDC1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2B9
Application*: WB, E
Target: SMNDC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0567
Application*: E, P, WB
Target: SMNDC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0566
Application*: E, IH, WB
Target: SMNDC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0565
Application*: E, IH, WB
Target: SMNDC1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-4415
Application*: E, P, WB
Target: SMNDC1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2E7
Application*: IP, E, WB
Target: SMNDC1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1A9
Application*: IP, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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