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SMNDC1

This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. [provided by RefSeq]

Full Name

SMNDC1

Function

Involved in spliceosome assembly.

Biological Process

Biological Process apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process mRNA processingIEA:UniProtKB-KW
Biological Process RNA splicing, via transesterification reactionsManual Assertion Based On ExperimentTAS:UniProtKB

Cellular Location

Nucleus speckle
Nucleus, Cajal body
Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies.

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Anti-SMNDC1 antibodies

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Human Recombinant SPF30 protein, His Tag (V2LY-0526-LY6924)

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Target: SMNDC1

Expressed Host: E. coli

Sequence: Amino Acid: 1-238

Tag: His Tag

Mouse Anti-SMNDC1 Recombinant Antibody (2B9) (CBMAB-A8372-LY)

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Target: SMNDC1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 2B9

Application*: WB, E

Mouse Anti-SMNDC1 (AA 1-239) Recombinant Antibody (CBXS-0567) (CBMAB-S3509-CQ)

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Target: SMNDC1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-0567

Application*: E, P, WB

Mouse Anti-SMNDC1 (AA 1-239) Recombinant Antibody (CBXS-0566) (CBMAB-S3508-CQ)

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Target: SMNDC1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-0566

Application*: E, IH, WB

Mouse Anti-SMNDC1 (AA 1-239) Recombinant Antibody (CBXS-0565) (CBMAB-S3507-CQ)

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Target: SMNDC1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-0565

Application*: E, IH, WB

Mouse Anti-SMNDC1 Recombinant Antibody (CBXS-4415) (CBMAB-S1657-CQ)

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Target: SMNDC1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXS-4415

Application*: E, P, WB

Mouse Anti-SMNDC1 Monoclonal Antibody (2E7) (CBMAB-0142-LY)

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Target: SMNDC1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 2E7

Application*: IP, E, WB

Mouse Anti-SMNDC1 Monoclonal Antibody (1A9) (CBMAB-0141-LY)

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Target: SMNDC1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 1A9

Application*: IP, E

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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