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SMNDC1

This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. [provided by RefSeq]
Full Name
SMNDC1
Function
Involved in spliceosome assembly.
Biological Process
Biological Process apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process mRNA processingIEA:UniProtKB-KW
Biological Process RNA splicing, via transesterification reactionsManual Assertion Based On ExperimentTAS:UniProtKB
Cellular Location
Nucleus speckle
Nucleus, Cajal body
Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies.

Anti-SMNDC1 antibodies

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Target: SMNDC1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2B9
Application*: WB, E
Target: SMNDC1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-4415
Application*: E, P, WB
Target: SMNDC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0565
Application*: E, IH, WB
Target: SMNDC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0566
Application*: E, IH, WB
Target: SMNDC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0567
Application*: E, P, WB
Target: SMNDC1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1A9
Application*: IP, E
Target: SMNDC1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2E7
Application*: IP, E, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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