loading...

SMPD2

This gene encodes a protein which was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase.

Full Name

sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)

Function

Catalyzes, at least in vitro, the hydrolysis of sphingomyelin to form ceramide and phosphocholine (PubMed:10608884).
Also hydrolyzes 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor) in vivo (PubMed:10608884).
Also acts on 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and sphingosylphosphocholine (PubMed:10608884, PubMed:14741383).

Biological Process

Biological Process ceramide biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process sphingolipid catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process sphingomyelin catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process sphingomyelin metabolic processManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane

View more

Anti-SMPD2 antibodies

+ Filters

Loading...

Mouse Anti-SMPD2 Recombinant Antibody (4A10) (CBMAB-A8387-LY)

Compare

Target: SMPD2

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 4A10

Application*: E, E

Mouse Anti-SMPD2 (AA 1-424) Recombinant Antibody (CBXS-0573) (CBMAB-S3515-CQ)

Compare

Target: SMPD2

Host: Mouse

Antibody Isotype: IgG3

Specificity: Human

Clone: CBXS-0573

Application*: E, IH, WB

Mouse Anti-SMPD2 Recombinant Antibody (CBXS-4465) (CBMAB-S1707-CQ)

Compare

Target: SMPD2

Host: Mouse

Antibody Isotype: IgG3, κ

Specificity: Human

Clone: CBXS-4465

Application*: E, P, WB

Rabbit Anti-SMPD2 Recombinant Antibody (CBWJN-1680) (CBMAB-N4306-WJ)

Compare

Target: SMPD2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse, Rat, Human

Clone: CBWJN-1680

Application*: WB, IP, IC

More Infomation

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

online inquiry

Online Inquiry