Tas2r121

Tas2r121 is a receptor that may function in the perception of bitterness and is gustducin-linked. It may function in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.

Full Name

Taste Receptor, Type 2, Member 121

Function

Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).

Biological Process

Biological Process detection of chemical stimulus involved in sensory perception of bitter tasteISO:MGI
Biological Process positive regulation of cytokinesisISO:MGI

Cellular Location

Cell membrane

Topology

Extracellular: 1-7
Helical: 8-28
Cytoplasmic: 29-43
Helical: 44-64
Extracellular: 65-88
Helical: 89-109
Cytoplasmic: 110-128
Helical: 129-149
Extracellular: 150-182
Helical: 183-203
Cytoplasmic: 204-232
Helical: 233-253
Extracellular: 254-262
Helical: 263-283
Cytoplasmic: 284-305