Tas2r121

Tas2r121 is a receptor that may function in the perception of bitterness and is gustducin-linked. It may function in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.

Full Name

Taste Receptor, Type 2, Member 121

Function

Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).

Biological Process

Biological Process detection of chemical stimulus involved in sensory perception of bitter tasteISO:MGI
Biological Process positive regulation of cytokinesisISO:MGI

Cellular Location

Cell membrane

Topology

Extracellular: 1-7
Helical: 8-28
Cytoplasmic: 29-43
Helical: 44-64
Extracellular: 65-88
Helical: 89-109
Cytoplasmic: 110-128
Helical: 129-149
Extracellular: 150-182
Helical: 183-203
Cytoplasmic: 204-232
Helical: 233-253
Extracellular: 254-262
Helical: 263-283
Cytoplasmic: 284-305

Anti-Tas2r121 antibodies

Mouse Anti-Tas2r121 Recombinant Antibody (CBYJT-1737) (CBMAB-T0798-YJ)

Datasheet

SDS

Target: Tas2r121

Host: Mouse

Antibody Isotype: IgG

Specificity: Mouse, Rat

Clone: CBYJT-1737

Application*: WB, IP, IF, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)