TDRD3

TDRD3 (Tudor Domain Containing 3) is a Protein Coding gene. Among its related pathways are Translational Control and Chromatin Regulation / Acetylation. Gene Ontology (GO) annotations related to this gene include chromatin binding. An important paralog of this gene is RMI1.
Full Name
TDRD3 Gene(Protein Coding) Tudor Domain Containing 3
Function
Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.
Biological Process
Biological Process chromatin organizationIEA:UniProtKB-KW
Biological Process DNA topological changeIC:ComplexPortal
Cellular Location
Cytoplasm
Nucleus
Predominantly cytoplasmic. Associated with actively translating polyribosomes and with mRNA stress granules.
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Anti-TDRD3 antibodies

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Target: TDRD3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-2464
Application*: IP
Target: TDRD3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: D3O2G
Application*: WB, IP
Target: TDRD3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey, Mouse, Rat
Clone: CBYJT-2466
Application*: IP, WB
Target: TDRD3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2465
Application*: IP
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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