TDRD3
TDRD3 (Tudor Domain Containing 3) is a Protein Coding gene. Among its related pathways are Translational Control and Chromatin Regulation / Acetylation. Gene Ontology (GO) annotations related to this gene include chromatin binding. An important paralog of this gene is RMI1.
Full Name
TDRD3 Gene(Protein Coding) Tudor Domain Containing 3
Function
Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.
Biological Process
Biological Process chromatin organizationIEA:UniProtKB-KW
Biological Process DNA topological changeIC:ComplexPortal
Biological Process DNA topological changeIC:ComplexPortal
Cellular Location
Cytoplasm
Nucleus
Predominantly cytoplasmic. Associated with actively translating polyribosomes and with mRNA stress granules.
Nucleus
Predominantly cytoplasmic. Associated with actively translating polyribosomes and with mRNA stress granules.
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Anti-TDRD3 antibodies
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Target: TDRD3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-2464
Application*: IP
Target: TDRD3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: D3O2G
Application*: WB, IP
Target: TDRD3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey, Mouse, Rat
Clone: CBYJT-2466
Application*: IP, WB
Target: TDRD3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2465
Application*: IP
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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