TESK2
This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis. [provided by RefSeq]
Full Name
testis-specific kinase 2
Function
Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis.
Biological Process
Biological Process actin cytoskeleton organizationSource:UniProtKB
Biological Process focal adhesion assemblySource:UniProtKB
Biological Process protein phosphorylationSource:UniProtKB
Biological Process spermatogenesisSource:UniProtKB
Biological Process focal adhesion assemblySource:UniProtKB
Biological Process protein phosphorylationSource:UniProtKB
Biological Process spermatogenesisSource:UniProtKB
Cellular Location
Nucleus
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Anti-TESK2 antibodies
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Target: TESK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 6C7
Application*: WB, E
Target: TESK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5H4
Application*: WB, E
Target: TESK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: V2-618562
Application*: WB, E
Target: TESK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5D1
Application*: WB, E
Target: TESK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5C3
Application*: WB, E
Target: TESK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1A8
Application*: WB, E
Target: TESK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-2562
Application*: E, IF, WB
Target: TESK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-2561
Application*: E, IF, P, WB
Target: TESK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-2560
Application*: E, WB
Target: TESK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-2559
Application*: E, IF, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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