TRAPPC10
TRAPPC10 is a transmembrane protein found in the cis-Golgi complex. TRAPPC10 is part of the multisubunit transport protein particle (TRAPP) complex and may be involved in vesicular transport from the endoplasmic reticulum to the Golgi. Mutations in this gene could be responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy, or for autoimmune polyglandular disease type 1.
Full Name
Trafficking Protein Particle Complex 10
Function
Specific subunit of the TRAPP (transport protein particle) II complex, a highly conserved vesicle tethering complex that functions in late Golgi trafficking as a membrane tether.
Biological Process
Biological Process early endosome to Golgi transport Source:GO_Central1 Publication
Biological Process endoplasmic reticulum to Golgi vesicle-mediated transport Source:ComplexPortal1 Publication
Biological Process intra-Golgi vesicle-mediated transport Source:GO_Central1 Publication
Biological Process vesicle coating Source:ComplexPortal1 Publication
Biological Process vesicle tethering Source:ComplexPortal1 Publication
Biological Process endoplasmic reticulum to Golgi vesicle-mediated transport Source:ComplexPortal1 Publication
Biological Process intra-Golgi vesicle-mediated transport Source:GO_Central1 Publication
Biological Process vesicle coating Source:ComplexPortal1 Publication
Biological Process vesicle tethering Source:ComplexPortal1 Publication
Cellular Location
Golgi apparatus, cis-Golgi network
Involvement in disease
Defects in this gene may cause an autosomal recessive disorder characterized by severe intellectual disability, poor speech and aggressive behavior.
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Anti-TRAPPC10 antibodies
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Target: TRAPPC10
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-4556
Application*: WB
Target: TRAPPC10
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-4555
Application*: E, WB
Target: TRAPPC10
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 5D5
Application*: WB, E
Target: TRAPPC10
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5B4
Application*: WB, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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