UTF1

The protein encoded by this gene is a leucine zipper-containing transcriptional coactivator that may link the upstream activator ATF2 with the basal transcription complex. The encoded protein is closely associated with chromatin and is required for the proper differentiation of embryonic carcinoma and embryonic stem cells. Diseases associated with UTF1 include Opportunistic Bacterial Infectious Disease and Nocardiosis. Among its related pathways are Wnt / Hedgehog / Notch and Oct4 in Mammalian ESC Pluripotency.

Undifferentiated Embryonic Cell Transcription Factor 1

Acts as a transcriptional coactivator of ATF2.

Biological Process male gonad development Source:UniProtKB1 Publication
Biological Process positive regulation of transcription by RNA polymerase II Source:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:ProtInc1 Publication

Nucleus

Phosphorylated.