VPREB1
The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Full Name
V-Set Pre-B Cell Surrogate Light Chain 1
Function
Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation.
Biological Process
Biological Process immune response Source:GO_Central1 Publication
Cellular Location
Endoplasmic reticulum
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Anti-VPREB1 antibodies
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Target: VPREB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2531
Application*: F
Target: VPREB1
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: R3/VpreB
Application*: F
Target: VPREB1
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: R3
Application*: F
Target: VPREB1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: HSL96
Application*: F, IP
Target: VPREB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4578
Application*: F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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