VPREB1

The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Full Name
V-Set Pre-B Cell Surrogate Light Chain 1
Function
Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation.
Biological Process
Biological Process immune response Source:GO_Central1 Publication
Cellular Location
Endoplasmic reticulum
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Anti-VPREB1 antibodies

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Mouse Anti-VPREB1 Recombinant Antibody (CBT2531) (V2LY-0625-LY1212)

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Target: VPREB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2531
Application*: F
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Rat Anti-VPREB1 Recombinant Antibody (R3/VpreB) (CBMAB-C12634-LY)

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Target: VPREB1
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: R3/VpreB
Application*: F
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Rat Anti-VPREB1 Recombinant Antibody (R3) (CBMAB-C12633-LY)

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Target: VPREB1
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: R3
Application*: F
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Mouse Anti-VPREB1 Recombinant Antibody (HSL96) (CBMAB-C5982WJ)

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Target: VPREB1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: HSL96
Application*: F, IP
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Mouse Anti-VPREB1 Recombinant Antibody (CBWJC-4578) (CBMAB-C5981WJ)

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Target: VPREB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4578
Application*: F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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