WFIKKN1

This gene encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. These domains have been implicated frequently in inhibition of various types of proteases, suggesting that the encoded protein may be a multivalent protease inhibitor and may control the action of multiple types of serine proteases as well as metalloproteinases.

WAP, Follistatin/Kazal, Immunoglobulin, Kunitz And Netrin Domain Containing 1

Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity (By similarity).

Biological Process muscle cell development Source:Ensembl
Biological Process negative regulation of DNA binding Source:Ensembl
Biological Process negative regulation of protein binding Source:Ensembl
Biological Process negative regulation of transforming growth factor beta receptor signaling pathway Source:UniProtKB1 Publication
Biological Process roof of mouth development Source:Ensembl
Biological Process skeletal system development Source:Ensembl

Secreted