ZNF217

Zinc-finger nucleases (ZFNs) are artificial restriction enzymes generated by fusing a zinc finger DNA-binding domain to a DNA-cleavage domain. Zinc finger domains can be engineered to target specific desired DNA sequences and this enables zinc-finger nucleases to target unique sequences within complex genomes. By taking advantage of endogenous DNA repair machinery, these reagents can be used to precisely alter the genomes of higher organisms. Alongside CRISPR/Cas9 and TALEN, ZFN is a prominent tool in the field of genome editing.
Full Name
ZNF217
Function
Binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at 'Ser-473'.
Biological Process
Biological Process negative regulation of DNA-templated transcription Source:UniProtKB1 Publication
Biological Process negative regulation of transcription by RNA polymerase II Source:NTNU_SB1 Publication
Biological Process regulation of DNA-templated transcription Source:UniProtKB1 Publication
Cellular Location
Nucleus
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Anti-ZNF217 antibodies

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Mouse Anti-ZNF217 Recombinant Antibody (5H9) (CBMAB-0887-LY)

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Target: ZNF217
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5H9
Application*: IP, M
Datasheet SDS

Mouse Anti-ZNF217 Recombinant Antibody (3C3) (CBMAB-0886-LY)

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Target: ZNF217
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 3C3
Application*: IP, M
Datasheet SDS

Mouse Anti-ZNF217 Recombinant Antibody (1G2) (CBMAB-0885-LY)

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Target: ZNF217
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1G2
Application*: IP, M
Datasheet SDS

Mouse Anti-ZNF217 Recombinant Antibody (1B10) (CBMAB-Z0422-WJ)

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Target: ZNF217
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1B10
Application*: WB, IH
Datasheet SDS

Mouse Anti-ZNF217 Recombinant Antibody (2B4) (CBMAB-Z0421-WJ)

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Target: ZNF217
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B4
Application*: WB, IH
Datasheet SDS

Mouse Anti-ZNF217 Recombinant Antibody (2B1) (CBMAB-Z0420-WJ)

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Target: ZNF217
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B1
Application*: WB, IH
Datasheet SDS

Mouse Anti-ZNF217 Recombinant Antibody (1G8) (CBMAB-Z0419-WJ)

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Target: ZNF217
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1G8
Application*: WB
Datasheet SDS

Mouse Anti-ZNF217 Recombinant Antibody (1D9) (CBMAB-Z0418-WJ)

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Target: ZNF217
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1D9
Application*: WB
Datasheet SDS

Mouse Anti-ZNF217 Recombinant Antibody (3G5) (CBMAB-Z0417-WJ)

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Target: ZNF217
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3G5
Application*: WB, IH
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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