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Mouse Anti-ADGRB3 Recombinant Antibody (V2-51279) (CBMAB-2087-YY)

This product is mouse antibody that recognizes ADGRB3. The antibody CBYY-1738 can be used for immunoassay techniques such as: WB
See all ADGRB3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-51279
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Mouse myeloma cell line NS0-derived recombinant human BAI3, Ala25-Thr880.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
IHC8-25 μg/ml
FC0.25 μg/10^6 cells

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, Trehalose
Preservative
None
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Adhesion G Protein-Coupled Receptor B3
Introduction
This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis.
Entrez Gene ID
577
UniProt ID
O60242
Alternative Names
Adhesion G Protein-Coupled Receptor B3; Brain-Specific Angiogenesis Inhibitor 3; BAI3; DJ91B17.1 (Brain-Specific Angiogenesis Inhibitor 3); KIAA0550;
Function
Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity (By similarity). Promotes myoblast fusion through ELMO/DOCK1.
Biological Process
Adenylate cyclase-activating G protein-coupled receptor signaling pathway
Cell surface receptor signaling pathway
G protein-coupled receptor signaling pathway
Maintenance of synapse structure
Motor learning
Myoblast fusion
Negative regulation of angiogenesis
Neuron remodeling
Positive regulation of synapse assembly
Regulation of dendrite morphogenesis
Cellular Location
Cell membrane
Topology
Extracellular: 25-880 aa
Helical: 881-901 aa
Cytoplasmic: 902-910 aa
Helical: 911-931 aa
Extracellular: 932-939 aa
Helical: 940-960 aa
Cytoplasmic: 961-981 aa
Helical: 982-1002 aa
Extracellular: 1003-1023 aa
Helical: 1024-1044 aa
Cytoplasmic: 1045-1098 aa
Helical: 1099-1119 aa
Extracellular: 1120-1125 aa
Helical: 1126-1146 aa
Cytoplasmic: 1147-1522 aa
PTM
The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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