Recombinant full length Human ARA9
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
The AHR-interacting protein (AIP) was originally cloned and designated XAP2 by Kuzhandaivelu et al. (1996) who used a yeast 2-hybrid system to identify proteins that interact with the hepatitis B virus (HBV) X protein. By use of a yeast 2-hybrid assay to detect proteins that interact with AHR in a ligand-dependent manner, Carver and Bradfield demonstrated interaction of AIP with AHR. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene. Using Northern blot analysis, Kuzhandaivelu et al. detected a 1.25-kb AIP transcript in all 16 adult tissues tested with the exception of the liver.
Aryl Hydrocarbon Receptor Interacting Protein; HBV X-Associated Protein 2; Immunophilin Homolog ARA9; XAP-2; XAP2; Aryl Hydrocarbon Receptor-Interacting Protein; Aryl-Hydrocarbon Receptor-Interacting Protein; FKBP16; FKBP37; SMTPHN; ARA9