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Mouse Anti-BCAS2 Recombinant Antibody (1D10) (CBMAB-A0729-LY)

The product is antibody recognizes BCAS2. The antibody 1D10 immunoassay techniques such as: WB, ELISA.
See all BCAS2 antibodies
Published Data
Fig. 1 Western blot
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Summary

Host Animal
Mouse
Specificity
Human
Clone
1D10
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
BCAS2 (NP_005863, 116 a.a. ~ 225 a.a) partial recombinant protein with GST tag.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
BCAS2, Pre-MRNA Processing Factor
Entrez Gene ID
10286
UniProt ID
O75934
Alternative Names
DAM1
Function
Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:28502770, PubMed:28076346, PubMed:29360106, PubMed:29301961, PubMed:30705154).
Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Biological Process
mRNA splicing, via spliceosome Source: UniProtKB
RNA splicing Source: UniProtKB
RNA splicing, via transesterification reactions Source: UniProtKB
Cellular Location
Nucleus; Nucleolus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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