Sign in or Register   Sign in or Register
  |  

Mouse Anti-C3AR1 Recombinant Antibody (CBXC-0014) (CBMAB-C3465-CQ)

This product is a mouse antibody that recognizes C3AR1. The antibody CBXC-0014 can be used for immunoassay techniques such as: FC, IHC.
See all C3AR1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXC-0014
Antibody Isotype
IgG1
Application
FC, IHC

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Complement C3a Receptor 1
Introduction
The C3a receptor also known as complement component 3a receptor 1 (C3AR1) is a G protein-coupled receptor protein involved in the complement system.
Entrez Gene ID
719
UniProt ID
Q16581
Alternative Names
AZ3B; C3AR; HNFAG09
Function
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
Biological Process
Blood circulation Source: ProtInc
Chemotaxis Source: UniProtKB-KW
Complement receptor mediated signaling pathway Source: UniProtKB
G protein-coupled receptor signaling pathway Source: Reactome
Inflammatory response Source: GO_Central
Neutrophil degranulation Source: Reactome
Phospholipase C-activating G protein-coupled receptor signaling pathway Source: GO_Central
Positive regulation of angiogenesis Source: Ensembl
Positive regulation of cytosolic calcium ion concentration Source: GO_Central
Positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling Pathway Source: UniProtKB
Positive regulation of macrophage chemotaxis Source: Ensembl
Positive regulation of neutrophil chemotaxis Source: Ensembl
Positive regulation of vascular endothelial growth factor production Source: Ensembl
Purinergic nucleotide receptor signaling pathway Source: Reactome
Regulation of complement activation Source: Reactome
Cellular Location
Cell membrane
Topology
Extracellular: 1-23 aa
Helical: 24-46 aa
Cytoplasmic: 47-57 aa
Helical: 58-80 aa
Extracellular: 81-96 aa
Helical: 97-118 aa
Cytoplasmic: 119-139 aa
Helical: 140-160 aa
Extracellular: 161-340 aa
Helical: 341-360 aa
Cytoplasmic: 361-377 aa
Helical: 378-400 aa
Extracellular: 401-417 aa
Helical: 418-438 aa
Cytoplasmic: 439-482 aa
PTM
Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin.
O-glycosylated.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-C3AR1 Recombinant Antibody (CBXC-0014)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare