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Mouse Anti-CACNG7 Recombinant Antibody (CBXC-0040) (CBMAB-C5207-CQ)

This product is a mouse antibody that recognizes CACNG7. The antibody CBXC-0040 can be used for immunoassay techniques such as: ELISA, WB.
See all CACNG7 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXC-0040
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 7
Introduction
CACNG7 (Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 7) is a Protein Coding gene. Among its related pathways are Cardiac conduction and NFAT and Cardiac Hypertrophy. Gene Ontology (GO) annotations related to this gene include voltage-gated calcium channel activity. An important paralog of this gene is CACNG5.
Entrez Gene ID
59284
UniProt ID
P62955
Alternative Names
Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 7; Neuronal Voltage-Gated Calcium Channel Gamma-7 Subunit; Calcium Channel, Voltage-Dependent, Gamma Subunit 7; Transmembrane AMPAR Regulatory Protein Gamma-7; TARP Gamma-7;
Function
Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (PubMed:21127204).
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity only for GRIA1 and GRIA2 (PubMed:21172611).
Biological Process
Calcium ion transport Source: UniProtKB
Cardiac conduction Source: Reactome
Neurotransmitter receptor internalization Source: GO_Central
Neurotransmitter receptor transport, postsynaptic endosome to lysosome Source: GO_Central
Positive regulation of dendrite extension Source: Ensembl
Positive regulation of synaptic transmission, glutamatergic Source: GO_Central
Postsynaptic neurotransmitter receptor diffusion trapping Source: GO_Central
Regulation of AMPA receptor activity Source: UniProtKB
Regulation of mRNA stability Source: Ensembl
Transmission of nerve impulse Source: GO_Central
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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