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Mouse Anti-CALB2 Recombinant Antibody (IHC523) (CBMAB-MA027-YC)

Provided herein is a Mouse monoclonal antibody against Calbindin 2. The antibody can be used for immunoassay techniques, such as IHC. And it gave a positive signal in Mesothelioma.
See all CALB2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
IHC523
Application
IHC (1:100 - 1:200)

Basic Information

Specificity
Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
Tris buffer pH 7.3 - 7.7, 1% BSA, < 0.1% Sodium Azide
Storage
Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

Target

Full Name
Calbindin 2
Introduction
CALB2 is an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers.
Entrez Gene ID
794
UniProt ID
P22676
Alternative Names
Calbindin 2; 29 KDa Calbindin; Calretinin; CAB29; CR; Testicular Secretory Protein Li 8;
Function
Calretinin is a calcium-binding protein which is abundant in auditory neurons.
Biological Process
Regulation of cytosolic calcium ion concentration Source: GO_Central
Regulation of long-term synaptic potentiation Source: GO_Central
Regulation of presynaptic cytosolic calcium ion concentration Source: GO_Central
Cellular Location
Cuticular plate; Cytosol; Nucleus; Synaptic membrane; Dendrite; Gap junction; Neuron projection; Parallel fiber to Purkinje cell synapse; Stereocilium; Synapse; Terminal bouton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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