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Mouse Anti-CAVIN3 Recombinant Antibody (8D3) (CBMAB-A7047-LY)

The product is antibody recognizes PRKCDBP. The antibody 8D3 immunoassay techniques such as: WB, ELISA.
See all CAVIN3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
8D3
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
PRKCDBP (NP_659477, 161 a.a. ~ 261 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Caveolae Associated Protein 3
Introduction
The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein. [provided by RefSeq]
Entrez Gene ID
112464
UniProt ID
Q969G5
Alternative Names
HSRBC; MGC20400; SRBC
Function
Regulates the traffic and/or budding of caveolae (PubMed:19262564).
Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by promoting the rapid release of caveolae from the cell surface. Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2 (By similarity).
Biological Process
Circadian regulation of gene expression Source: UniProtKB
Cellular Location
Cytoplasm; Cytosol; Caveola. Localizes in the caveolae in a caveolin-dependent manner.
PTM
In vitro, phosphorylated by PRKCD.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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