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Mouse Anti-Cd44 Recombinant Antibody (3H2606) (CBMAB-L2938-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Cd44 Antigen (Cd44). The antibody can be used for immunoassay techniques, such as FC.
Host Species
Mouse
Application
FC
Immunogen
Spleen cells from B6PL-Ly-2a/Ly-3a B6-Ly-1a mice.
Antibody Isotype
IgG1
Specificity
Mouse
Cross Reactivity
Mouse
Clone
3H2606
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
CD44 antigen is a receptor for hyaluronic acid (HA). It mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, CD44 may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. CD44 is a receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function.
Alternative Name
Ly-24; Pgp-1; HERMES; AU023126; AW121933; AW146109; CD44 antigen; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; PGP-I; extracellular matrix receptor III; hermes antigen; hyaluronate receptor; lymphocyte antigen 24; phagocytic glycoprotein 1; phagocytic glycoprotein I
Entrez Gene ID
UniProt ID
Cat CBMAB-L2938-YJ
Conjugates
Size
Price $
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