Sign in or Register   Sign in or Register
  |  

Mouse Anti-CDK11A (AA 681-780) Recombinant Antibody (CBFYC-1590) (CBMAB-C1649-FY)

This product is mouse antibody that recognizes CDK11A. The antibody CBFYC-1590 can be used for immunoassay techniques such as: ELISA, IF.
See all CDK11A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-1590
Antibody Isotype
IgG2a, k
Application
ELISA, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 681-780

Target

Full Name
Cyclin Dependent Kinase 11A
Introduction
CDK11A (Cyclin Dependent Kinase 11A) is a Protein Coding gene. Diseases associated with CDK11A include Neuroblastoma. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDK11B.
Entrez Gene ID
728642
UniProt ID
Q9UQ88
Alternative Names
Cyclin Dependent Kinase 11A; Galactosyltransferase-Associated Protein Kinase P58/GTA; Cell Division Cycle 2-Like 2 (PITSLRE Proteins); PITSLRE Serine/Threonine-Protein Kinase CDC2L2; Cell Division Cycle 2-Like Protein Kinase 2; Cell Division Protein Kinase 11A; EC 2.7.11.22; CDC2L2; CDC2L3; PITSLRE Protein Kinase Beta SV16 Isoform; PITSLRE Protein Kinase Beta SV17 Isoform; PITSLRE Protein Kinase Beta SV18 Isoform; PITSLRE Protein Kinase Beta SV1 Isoform; PITSLRE Protein Kinase Beta SV2 Isoform
Function
Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.
Biological Process
Apoptotic process Source: UniProtKB
Mitotic cell cycle Source: UniProtKB
Protein phosphorylation Source: UniProtKB
Regulation of cell growth Source: UniProtKB
Regulation of mitotic cell cycle Source: GO_Central
Regulation of mRNA processing Source: UniProtKB
Regulation of transcription, DNA-templated Source: UniProtKB
Cellular Location
Cytoplasm; Nucleus
PTM
During apoptosis, induced by Fas or tumor necrosis factor, specific CKD11 p110 isoforms are cleaved by caspases to produce a protein (p110C) that contains the C-terminal kinase domain of the CDK11 proteins.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-CDK11A (AA 681-780) Recombinant Antibody (CBFYC-1590)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare