Mouse Anti-CDKL1 Recombinant Antibody (CBYY-C1791) (CBMAB-C3229-YY)

This product is mouse antibody that recognizes CDKL1. The antibody CBYY-C1791 can be used for immunoassay techniques such as: ELISA, WB
See all CDKL1 antibodies

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBYY-C1791

Antibody Isotype

IgG1, κ

Application

ELISA, WB

Basic Information

Immunogen

Recombinant protein corresponding to aa259-358 from human CDKL1 with GST tag. MW of the GST tag alone is 26kD

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Preservative

PBS, pH 7.4

Concentration

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Cyclin Dependent Kinase Like 1

Entrez Gene ID

8814

UniProt ID

Q00532

Alternative Names

Cerebral Dopamine Neurotrophic Factor; Conserved Dopamine Neurotrophic Factor; Arginine-Rich, Mutated In Early Stage Tumors-Like 1; ARMET-Like Protein 1; ARMETL1;

Biological Process

Heart development Source: Ensembl
Protein phosphorylation Source: GO_Central
Regulation of cilium assembly Source: UniProtKB

Cellular Location

Nucleus; Cytoplasm

References

Shao, S., Ju, M., Lei, J., Lu, X., Li, H., Wang, D., & Xia, C. (2021). Egr‑1 inhibits colon cancer cell proliferation, migration and invasion via regulating CDKL1 at the transcriptional level. Oncology Reports, 46(2), 1-9.

Lu, M., Xiong, H., Xia, Z. K., Liu, B., Wu, F., Zhang, H. X., ... & Liu, P. (2021). circRACGAP1 promotes non-small cell lung cancer proliferation by regulating miR-144-5p/CDKL1 signaling pathway. Cancer Gene Therapy, 28(3), 197-211.

Li, W., Cao, J., Liu, J., Chu, W., Zhang, C., Chen, S., & Kang, Z. (2019). Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion. Cellular & molecular biology letters, 24(1), 1-11.

Li, K., Meng, Z., Jiang, L., Xia, C., Xu, K., Yuan, D., ... & Liu, S. (2019). CDKL1 promotes the chemoresistance of human oral squamous cell carcinoma cells to hydroxycamptothecin. Molecular and cellular probes, 44, 57-62.

Rout, A. K., Dehury, B., Maharana, J., Nayak, C., Baisvar, V. S., Behera, B. K., & Das, B. K. (2018). Deep insights into the mode of ATP-binding mechanism in Zebrafish cyclin-dependent protein kinase-like 1 (zCDKL1): A molecular dynamics approach. Journal of Molecular Graphics and Modelling, 81, 175-183.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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