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Mouse Anti-CEACAM16 Recombinant Antibody (CBLC144-LY) (CBMAB-C10864-LY)

The product is antibody recognizes CEACAM16. The antibody CBLC144-LY immunoassay techniques such as: WB, IP, IF, ELISA.
See all CEACAM16 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBLC144-LY
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Carcinoembryonic Antigen Related Cell Adhesion Molecule 16
Introduction
The protein encoded by this gene is a secreted glycoprotein that in mouse interacts with tectorial membrane proteins in the inner ear. The encoded adhesion protein is found in cochlear outer hair cells and appears to be important for proper hearing over an extended frequency range. Defects in this gene likely are a cause of non-syndromic autosomal dominant hearing loss. [provided by RefSeq, May 2012]
Entrez Gene ID
Human388551
Mouse330483
Rat292700
UniProt ID
HumanQ2WEN9
MouseE9QA28
RatD3ZQE1
Function
Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane.
Biological Process
Sensory perception of sound Source: UniProtKB
Cellular Location
Secreted. Localizes to the tip of cochlear outer hair cells and to the tectorial membrane.
Involvement in disease
Deafness, autosomal dominant, 4B (DFNA4B): A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
Deafness, autosomal recessive, 113 (DFNB113): A form of non-syndromic, sensorineural deafness characterized by postlingual progressive hearing impairment. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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