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Mouse Anti-CELA1 Recombinant Antibody (CBYC-P047) (CBMAB-P0217-YC)

Provided herein is a Mouse monoclonal antibody against Human Chymotrypsin Like Elastase Family Member 1. The antibody can be used for immunoassay techniques, such as WB, ICC, IHC-P, IHC-Fr, ELISA.
See all CELA1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYC-P047
Antibody Isotype
IgG
Application
WB, ICC, IHC-P, IHC-Fr, ELISA

Basic Information

Immunogen
Elastase 1, Pancreatic
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.4, containing 0.02% sodium azide, 50% glycerol
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Chymotrypsin Like Elastase Family Member 1
Introduction
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B.
Entrez Gene ID
1990
UniProt ID
Q9UNI1
Alternative Names
Chymotrypsin Like Elastase Family Member 1; Elastase 1, Pancreatic; Pancreatic Elastase 1; EC 3.4.21.36; Elastase-1; ELA1; Chymotrypsin-Like Elastase Family, Member 1; Chymotrypsin-Like Elastase Family Member 1; EC 3.4.21;
Function
Acts upon elastin.
Biological Process
Elastin catabolic process Source: Ensembl
Exocrine pancreas development Source: Ensembl
Inflammatory response Source: Ensembl
Multicellular organism growth Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: Ensembl
Pancreas morphogenesis Source: Ensembl
Positive regulation of angiogenesis Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: Ensembl
Post-embryonic development Source: Ensembl
Proteolysis Source: GO_Central
Regulation of cell differentiation Source: Ensembl
Regulation of cell population proliferation Source: Ensembl
Tissue remodeling Source: Ensembl
Wnt signaling pathway Source: Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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