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Mouse Anti-CELSR3 Recombinant Antibody (2F7) (CBMAB-C5114-LY)

This product is antibody recognizes CELSR3. The antibody 2F7 immunoassay techniques such as: ELISA, WB.
See all CELSR3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2F7
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa71-180 from human CELSR3 (NP_001398) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Cadherin EGF LAG Seven-Pass G-Type Receptor 3
Introduction
This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013]
Entrez Gene ID
UniProt ID
Alternative Names
Cadherin EGF LAG Seven-Pass G-Type Receptor 3; Multiple Epidermal Growth Factor-Like Domains Protein 2; Adhesion G Protein-Coupled Receptor C3; Epidermal Growth Factor-Like Protein 1; Multiple EGF-Like Domains Protein 2; Cadherin Family Member 11; Flamingo Homolog 1; EGF-Like Protein 1; CDHF11; HFMI1; EGFL1; MEGF2;
Function
Receptor that may have an important role in cell/cell signaling during nervous system formation.
Biological Process
Cell-cell adhesion Source: GO_Central
G protein-coupled receptor signaling pathway Source: GDB
Homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro
Multicellular organism development Source: UniProtKB-KW
Wnt signaling pathway, planar cell polarity pathway Source: ParkinsonsUK-UCL
Cellular Location
Cell membrane
Topology
Extracellular: 33-2540
Helical: 2541-2561
Cytoplasmic: 2562-2572
Helical: 2573-2593
Extracellular: 2594-2601
Helical: 2602-2622
Cytoplasmic: 2623-2643
Helical: 2644-2664
Extracellular: 2665-2681
Helical: 2682-2702
Cytoplasmic: 2703-2725
Helical: 2726-2746
Extracellular: 2747-2753
Helical: 2754-2774
Cytoplasmic: 2775-3312
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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