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Mouse Anti-CFHR2 Recombinant Antibody (06) (CBMAB-C1813-LY)

This product is antibody recognizes CFHR2. The antibody 06 immunoassay techniques such as: ELISA(Det).
See all CFHR2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
06
Antibody Isotype
IgG
Application
ELISA(Det)

Basic Information

Immunogen
Recombinant Human CFHR2 Protein
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Complement Factor H Related 2
Introduction
This gene belongs to a family of complement factor H-related genes (CFHR), which are clustered together with complement factor H gene on chromosome 1, and are involved in regulation of complement. Mutations in CFHR genes have been associated with dense deposit disease and atypical haemolytic-uraemic syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015]
Entrez Gene ID
3080
UniProt ID
P36980
Alternative Names
Complement Factor H Related 2; H Factor (Complement)-Like 3; H Factor-Like Protein 2; H Factor-Like 3; DDESK59; CFHL2; FHR-2;
Function
Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.
Biological Process
Cytolysis by host of symbiont cells Source: UniProtKB
Negative regulation of protein binding Source: UniProtKB
Regulation of complement activation Source: Reactome
Cellular Location
Secreted
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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