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Mouse Anti-CGB3 Antibody (4BA1) (CBMAB-1057CQ)

This product is a mouse antibody that recognizes CGB3. The antibody 4BA1 can be used for immunoassay techniques such as: ELISA.
See all CGB3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4BA1
Antibody Isotype
IgG
Application
ELISA

Basic Information

Immunogen
Synthetic Peptide (VLQGVLPALPQVVCNYR)
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 312-323

Target

Full Name
Chorionic Gonadotropin, beta polypeptide Peptide 1
Introduction
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. Diseases associated with CGB3 include Endodermal Sinus Tumor and Ectopic Pregnancy. Among its related pathways are Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors and Peptide hormone metabolism.
Entrez Gene ID
1082
UniProt ID
P01233
Alternative Names
CGB; CGB5; CGB7; CGB8; hCGB
Function
Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
Biological Process
Apoptotic process Source: ProtInc
Cell-cell signaling Source: ProtInc
Female gamete generation Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Hormone-mediated signaling pathway Source: GO_Central
Peptide hormone processing Source: Reactome
Regulation of transcription by RNA polymerase II Source: Reactome
Signal transduction Source: ProtInc
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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