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CGB3

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.
Full Name
Chorionic Gonadotropin, beta polypeptide Peptide 1
Function
Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
Biological Process
Apoptotic process Source: ProtInc
Cell-cell signaling Source: ProtInc
Female gamete generation Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Hormone-mediated signaling pathway Source: GO_Central
Peptide hormone processing Source: Reactome
Regulation of transcription by RNA polymerase II Source: Reactome
Signal transduction Source: ProtInc
Cellular Location
Secreted

Anti-CGB3 antibodies

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Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2609
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJC-2591
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-2585
Application*: E, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2583
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2580
Application*: C, P, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2579
Application*: P
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2605
Application*: E, IH, IP, R
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2604
Application*: E, IP, R, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2603
Application*: E, R
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2602
Application*: E, IA, P
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2600
Application*: E, IH
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2598
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2597
Application*: P
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2594
Application*: F
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2569
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2568
Application*: R, F
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HCGb/54+ HCGb/459
Application*: WB, P, C
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2028
Application*: E, IC, IF, C, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJC-2593
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJC-2578
Application*: IC, E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2577
Application*: IC, E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2576
Application*: C, P
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2573
Application*: E, P
Target: CGB3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBXC-1424
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0405
Application*: E, R, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2094
Application*: WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-0404
Application*: IH
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2572
Application*: E, F
Target: CGB3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CG04 + CG05
Application*: P, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0403
Application*: P, IP
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2395
Application*: WB, IH
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-3103
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HCG-8
Application*: IP
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2570
Application*: F
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 28A4
Application*: SE
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-1789
Application*: IH
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1788
Application*: WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1787
Application*: IH, IP
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1786
Application*: E, LF
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-1785
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1784
Application*: P, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1783
Application*: E, IF, C, P
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-0500
Application*: E, F
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0492
Application*: SE
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-2158
Application*: E, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2963
Application*: E, C, P
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: SPM105
Application*: WB, E, P, C
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: HCGb/54
Application*: WB, P, C
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HCGb/211
Application*: C
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: HCG-61
Application*: E, IF
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HCG-60
Application*: E, IF
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-0094
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-0093
Application*: WB, P, PE
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-0092
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYH-0091
Application*: E, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0090
Application*: E, IF, C, P
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2946
Application*: EIA, R, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: P3G7
Application*: E, IP, R
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: INN-hCG-22
Application*: E, P, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 4BA1
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: INN-hCG-24
Application*: E, RD
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: INN-hCG-53
Application*: WB, E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 34P2C2
Application*: E, IP, R, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2944
Application*: E, P, R
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-2945
Application*: E, IF
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: HCGb/459
Application*: E, P
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: INN-hCG-106
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 0.N.215 + 0.N.216
Application*: IH
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 27E8
Application*: SE
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 057-10019
Application*: ED, E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 057-10020
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10K154
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 12H18
Application*: E, LF
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 13F30
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 16k68
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2092
Application*: E, IC/IF, P, C
Target: CGB3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2D6B8
Application*: E, C, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 7H4
Application*: E, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C1937
Application*: E, WB
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10K153
Application*: IH, IP
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: h6
Application*: E, P
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: INN-hCG-45
Application*: E, R
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: n.a
Application*: E
Target: CGB3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2C5
Application*: IH
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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