CGB3

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.
Full Name
Chorionic Gonadotropin, beta polypeptide Peptide 1
Function
Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
Biological Process
Apoptotic process Source: ProtInc
Cell-cell signaling Source: ProtInc
Female gamete generation Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Hormone-mediated signaling pathway Source: GO_Central
Peptide hormone processing Source: Reactome
Regulation of transcription by RNA polymerase II Source: Reactome
Signal transduction Source: ProtInc
Cellular Location
Secreted
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Anti-CGB3 antibodies

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Mouse Anti-CGB3 Recombinant Antibody (28A4) (CBMAB-C0111-CQ)

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Target: CGB3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 28A4
Application*: E
Datasheet SDS

Mouse Anti-CGB3 Recombinant Antibody (CBFYC-0492) (CBMAB-C0542-FY)

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Target: CGB3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-0492
Application*: P
Datasheet SDS

Rabbit Anti-CGB3 Recombinant Antibody (CBFYH-0094) (CBMAB-H0951-FY)

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Target: CGB3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-0094
Application*: E
Datasheet SDS

Rabbit Anti-CGB3 Recombinant Antibody (CBFYH-0093) (CBMAB-H0950-FY)

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Target: CGB3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-0093
Application*: E
Datasheet SDS

Mouse Anti-CGB3 Recombinant Antibody (CBFYH-0092) (CBMAB-H0949-FY)

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Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0092
Application*: E, IP
Datasheet SDS

Mouse Anti-CGB3 Recombinant Antibody (CBFYH-0091) (CBMAB-H0948-FY)

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Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0091
Application*: E
Datasheet SDS

Mouse Anti-CGB3 Recombinant Antibody (CBFYH-0090) (CBMAB-H0947-FY)

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Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0090
Application*: E
Datasheet SDS

Mouse Anti-CGB3 Monoclonal Antibody (CBFYH-2946) (CBMAB-H0946-FY)

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Target: CGB3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-2946
Application*: WB, E
Datasheet SDS

Mouse Anti-CGB3 Monoclonal Antibody (CBFYH-2945) (CBMAB-H0940-FY)

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Target: CGB3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-2945
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Anti-CGB3 Monoclonal Antibody (CBFYH-2944) (CBMAB-H0939-FY)

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Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2944
Application*: WB, E, IP
Datasheet SDS

Mouse Anti-CGB3 Recombinant Antibody (CBT4506) (V2LY-0625-LY510)

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Target: CGB3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4506
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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